Cardiovascular Diseases, Ischemic Stroke, Vascular Diseases
Conditions
Keywords
stroke network, acute stroke care, emergency medical services, integrated care
Brief summary
FAST is an investigator-initiated multicenter study embedded in a German multistate acute stroke network. The main objectives of the FAST study are to improve outcomes and quality of care for stroke patients, to quantify the number of patients in need of thrombectomy within an integrated stroke network, to study the best way of delivering and performing thrombectomy and to investigate the best model of pre-hospital selection and referral for stroke patients.
Detailed description
Since 2015, mechanical thrombectomy in patients with large vessel occlusion has become an evidence based highly efficient treatment. In contrast to thrombolysis, thrombectomy can only be delivered by qualified interventionalists at comprehensive stroke centers. Thus, the implementation of thrombectomy into clinical practice remains a challenge. The investigators aim to establish a population based approach within a patient registry in a federal state overarching regional stroke network covering over 4 million inhabitants and integrating approximately 30 hospitals with different levels of expertise. The registry will include data from all acute ischemic stroke patients - approx. 12.000 patients p.a - within the network. The investigators plan to establish a central multi-interface platform integrating clinical data from the prehospital, intrahospital and rehabilitation phase including mandatory quality assurance, neurological and neuroradiological treatment and outcome data. The registry will allow addressing important questions, such as how many patients are candidates for thrombectomy, how many resources are needed to meet that demand and how treatment procedures and times can be improved. The overarching aim is to deliver high quality stroke care to every patient in the region.
Interventions
Observational study without study related intervention
Sponsors
Dietmar Hopp Stiftung
University Hospital Heidelberg
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years or older * Patients with ischemic stroke who are admitted to one of the hospitals of the Stroke Consortium Rhein-Neckar (FAST) * informed consent
Exclusion criteria
* no informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional outcome | 3 months after intervention | Functional outcome according to the modified Rankin Scale (mRS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients receiving acute recanalisation therapies of all referrals | 24 h after stroke onset | Number of patients receiving thrombolysis and/or thrombectomy of all patients included in to the Network via the database. |
| Referral rates | Stroke onset to discharge from acute hospital; through study completion, an average of 2 years | Referral rates by stroke service level (i.e. type of treatment center) |
Countries
Germany
Contacts
Primary ContactLoraine Busetto, Dr.
Backup ContactMaja Zenz, PhD
Outcome results
None listed