Comparison of Two Initial Evaluation Scales of the Severity of Brain Injury Adults Patients on the Neurological Outcome at 6 Months

Comparison of Two Initial Evaluation Scales of the Severity of Brain Injury Adults

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03157453

Acronym

CASSANDRA

Enrollment

367

Registered

2017-05-17

Start date

2017-08-07

Completion date

2022-12-02

Last updated

2024-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Injury

Keywords

Evaluation scale, Brain injury, Severity of Brain Injury, Initial Evaluation

Brief summary

Prospective cohort study. Any patient with potential cerebral injured (medical or traumatic) will be included in the study, regardless of its severity, history, the presence of anticoagulant or antiagrégant. The collection should be done as soon as possible, in the reception of vital emergencies or in the urgencies. The collection consists of the realization of a Glasgow score and a scale of Kremlin-Bicêtre for all patients by completing a standardized collection sheet. The collection of GCS and Kremlin-Bicêtre must be did at the same time. The collection sheet is filled by medical personnel trained. The future of the patient is informed at 6 months using the Glasgow Outcome Scale- Extended, which will be made during a following consultation or by phone. Additional data will be collected on the folder (ventilation time, days of hospitalization, mortality).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients aged 18 years or more * Potentially Victim of a cerebral injury whatever the level of severity * Having a calculation of GCS and KBS on arrival at the hospital (emergency room) * Affiliated to a social security scheme or benefiting through a third person.

Exclusion criteria

* Pregnant women * Patients who refusing to participate in research * Patients undergoing enhanced protection (persons deprived of liberty by a judicial or administrative decision, adults under legal protection).

Design outcomes

Primary

Measure	Time frame
Comparison of ROC curve areas of the two scales to predict an unfavorable neurological prognosis at 6 months (GOS-E < or = 5)	6 months

Secondary

Measure	Time frame
Comparison of ROC curve areas of the two scales to predict an unfavorable neurological prognosis at 6 months (GOS-E < or = 5) for traumatized cranial	6 months
Mortality in intensive care unit	6 months
Duration of stay in intensive care unit	6 months
Comparison of ROC curve areas of the two scales to predict an unfavorable neurological prognosis at 6 months (GOS-E < or = 5) for medical injury	6 months
Mortality at hospital	6 months
Mortalit at 6 months	6 months
Duration of stay at hospital	6 months
Duration of mechanical ventilation	6 months

Countries

France

Outcome results