Qp/Qs Ratio by Noninvasive Methods in Children With Shunt Dependent Pulmonary Circulation

The Accuracy of Qp/Qs Calculated by Noninvasive Methods in Children With Shunt Dependent Pulmonary Circulation

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03156764

Enrollment

Registered

2017-05-17

Start date

2017-05-23

Completion date

2020-07-21

Last updated

2021-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, General, Blood Gas Analysis, Blood Gas Monitoring, Transcutaneous, Congenital Heart Disease

Keywords

Qp/Qs ratio, Pediatric congenital heart disease

Brief summary

In pediatric cardiac patients with shunt dependent pulmonary circulation, Qp/Qs ratio is a important parameter indicating the balance of pulmonaty and systemic circulation. This study will calculate Qp/Qs using variables measured using non-invasive monitors (cerebral oximeter and pulse oximeter). This value will be compared with Qp/Qs calculated using variables obtained from blood sample.

Detailed description

Blood sampling will be performed in both arterial and central venous lines.

Interventions

OTHERQp/Qs ratio monitoring

Op/Qs -monitor will be calculated using SpO2 and cerebral oximetry Op/Qs -blood will be calculated using ABGA and VBGA

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 18 Years

Healthy volunteers

Inclusion criteria

1. pediatric cardiac patients scheduled to cardiac operation (shunt dependent pulmonary circulation) 2. preoperative SpO2\<97%

Exclusion criteria

1. unable to measure pulse oximeter or cerebral oximeter signal 2. unable to measure SaO2 or SmvO2 3. unstable vital sign

Design outcomes

Primary

Measure	Time frame	Description
the difference between Qp/Qs-monitor and Qp/Qs-blood	within 1 week after surgery	the difference between Qp/Qs-monitor (measure by pulse oximeter and NIRS) and Qp/Qs-blood (measured by blood gas analysis)

Secondary

Measure	Time frame	Description
the difference between SpO2 and SaO2	within 1 week after surgery	the difference between SpO2 (measure by pulse oximeter)and SaO2 (measured by blood gas analysis)
the difference between cerebral oximeter score and and SmvO2	within 1 week after surgery	the difference between cerebral oximeter (measure by NIRS)and SmvO2 (measured by blood gas analysis)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026