Lung Collapse
Conditions
Brief summary
This study aims to compared the effects of high flow nasal during the induction and during the weaning of anesthesia on intraoperative and postoperative oxygenation and postoperative atelectasis in obese patients undergoing bariatric surgery versus the standard of care, which consists in supplemental oxygen with face mask (Venturi mask).
Interventions
PROCEDUREHFNC group
Positive pressure plus supplemental oxygen through a high flow nasal oxygen device
PROCEDUREStandard group
Supplemental oxygen through venturi mask
Sponsors
Fundación para la Investigación del Hospital Clínico de Valencia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Body mass index \> 35 Kg/m2 * Bariatric surgery * Informed consent signed
Exclusion criteria
* age \<18yr or \>80yr * pregnancy or breast-feeding status * patients with previous known respiratory disease * hemodynamic instability at entry (need of vasopressors or ionotropes at entry or a ventricular assist device
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxygenation | intraoperative | The oxygenation (the ratio of partial pressure of arterial oxygen with inspiratory oxygen fraction, PaO2/FIO2) informs of the percentadge of shunt. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oxygenation | First 24 postoperative hours | PaO2/FIO2 |
| Atelectasis | First 24 postoperative hours | Atelectasis evaluated with X-ray |
Countries
Spain
Outcome results
None listed