Fish, Polyunsaturated Fatty Acids Intake and Mortality

Fish, Polyunsaturated Fatty Acids Intake and Mortality: Analysis of CHNS and NHANES

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03155659

Enrollment

50145

Registered

2017-05-16

Start date

1989-01-31

Completion date

2012-07-31

Last updated

2024-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mortality, Polyunsaturated Fatty Acids

Keywords

Fish, Polyunsaturated fatty acids, Mortality, CHNS, NHANES

Brief summary

Data linking fish, polyunsaturated fatty acids intake and mortality are lacking and conflicting. We aim to use data from the China Health and Nutrition Survey (CHNS) and National Health and Nutrition Examination Survey (NHANES) to investigate the associations of fish and polyunsaturated fatty acids (PUFA) intake with mortality in Chinese and US populations. The study findings will be informative for addressing the role of fish and specific PUFA in human health and improve basis for dietary recommendations.

Detailed description

Data from the China Health and Nutrition Survey (CHNS, from 1989 to 2011) and National Health and Nutrition Examination Survey (NHANES), including NHANES III conducted in 1988-1994 and continuous NHANES 1999-2010 were used to investigate the associations of fish and polyunsaturated fatty acids intake with mortality.The following variables were used: 1. Demographics: age, sex, race/ethnicity, residence 2. Socioeconomic variables: education, marital status, 3. Dietary variables: Intakes of fish, polyunsaturated fatty acids, total energy, vegetables, fruits, red meat and saturated fat 4. Clinical assessments: hypertension, diabetes, cancer, cardiovascular disease (CVD), family history of CVD

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adults aged ≥20 with complete data on diet and follow-up time

Exclusion criteria

* Missing information for mortality * Cardiovascular disease * Cancer

Design outcomes

Primary

Measure	Time frame	Description
Total Mortality	From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years	Total Mortality from All Causes

Secondary

Measure	Time frame	Description
Cause-specific mortality	From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years	Cause-specific mortality from diseases

Outcome results