Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03155555

Enrollment

Registered

2017-05-16

Start date

2016-12-31

Completion date

2017-12-17

Last updated

2019-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Endotracheal, Anesthesia, General, Fluid Responsiveness, Mechanical Ventilation

Keywords

Fluid Responsiveness, Pediatric surgery, General endotracheal anaesthesia

Brief summary

The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index of fluid responsiveness in mechanically ventilated children intra-operatively.

Interventions

OTHERMeasurement of aortic and carotid Doppler peak systolic velocity variation

Aortic peak systolic velocity variation to be measured by echocardiography from apical five chamber and suprasternal windows alongwith carotid peak systolic velocity variation by Doppler ultrasound simultaneously at intermittent time points intermittently.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Years to 12 Years

Healthy volunteers

Inclusion criteria

• Patients scheduled for mon-cardiac surgeries under general endotracheal anaesthesia in supine position with expected duration more than 1 hour

Exclusion criteria

* Known congenital heart disease * Any non-sinus rhythm, arrhythmias * Patients on vasoactive medications * Chest wall deformities, situs non solitus (eg. dextrocardia) * Patients scheduled for open chest surgeries * History of neck surgery/ carotid interventions

Design outcomes

Primary

Measure	Time frame	Description
Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation	Measurements made within 3 minutes	Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation by Bland-Altman analysis

Secondary

Measure	Time frame	Description
Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows	Measurements made within 3 minutes	Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows by Bland-Altman analysis

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026