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Infants Colics : Towards a Migrainous Origin ?

Association Between Infant Colics and Parental Migraine ? Non Interventional Study in the Pediatric Emergency Unit of Nancy (France) University Hospital

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03155360
Acronym
COLIGRAINE
Enrollment
300
Registered
2017-05-16
Start date
2017-05-18
Completion date
2017-11-01
Last updated
2017-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colic, Infantile, Migraine, Migraine Equivalents

Keywords

Colics, infant colics, Migraine equivalent, Migraine, Episodic symptoms associated to migraine, Colic

Brief summary

According to recent studies, we want to find evidences that infant colics could be a episodic symptom associated to migraine as cyclic vomiting syndrome or abdominal migraine are. The main purpose is to compare the presence of colics in infants between 60 days and 180 days of life and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents.

Detailed description

Recent studies shows that : * Infants with colics have more probability to become migrainous when they will grow up * Migrainous children have more colic history in their past * Migrainous parents have more babies with colics than non-migrainous parents According to these studies, we want to find othen evidences that infant colics could be a migraine equivalent as cyclic vomiting syndrome or abdominal migraine are. Recently, the international classification of headache disease IIIbeta added in its appendix colics in the episodic symptoms associated to migraine The main purpose of our study in the pediatric emergency unit of Nancy is to compare the presence of colics in infants and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents. The data collection will be made thanks to a survey which will be completed by the parents.

Interventions

OTHERNon interventional study

Non interventional study

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Days to 180 Days

Inclusion criteria

* All infants between 60 days and 180 days of life who comes to the Nancy University Hospital pediatric emergency unit

Exclusion criteria

* Language barrier of parents

Design outcomes

Primary

MeasureTime frameDescription
Proportion of real colics according to Wessel definitionAt the inclusion
Proportion of migrainous parentsAt the inclusionProportion of migrainous parents in each group

Secondary

MeasureTime frameDescription
Proportion of partenal migraineAt the inclusion
Age of begining of colicsAt the inclusionaverage and median age
Proportion of Infant colics according the feeling parentsAt the inclusion
Proportion of real colics according to Wessel definition in the subgroup of parents who report that their child has colicat the inclusion
Age of ending of colicsAt the inclusionaverage and median age
Proportion of maternal migraineAt the inclusion

Countries

France

Contacts

Primary ContactFrançois BREZIN
francois.brezin@gmail.com00 33 6 63 78 08 87
Backup ContactAnne BORSA-DORION
a.borsa-dorion@chru-nancy.fr00 33 3 83 15 47 33

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026