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Different Crystalloids on AKI in Shock

The Effect of Different Crystalloids on the Incidence of Acute Kidney Injury in Shock Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03155126
Enrollment
600
Registered
2017-05-16
Start date
2017-06-30
Completion date
2018-07-31
Last updated
2017-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shock

Keywords

shock, acute kidney injury, crystalloid

Brief summary

The goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Detailed description

Fluid resuscitation is important to shock patients. Saline is the classical fluids for resuscitation. However, studies showed that resuscitation with saline could increase the incidence of hyperchloremia and acute kidney injury. Thus, the goal is to observe that the incidence of acute kidney injury in patients who need fluid resuscitation when resuscitated with saline or acetated Ringer's sodium.

Interventions

OTHERFluid resuscitation

Patients in the saline group were resuscitated with saline, patients in the other group were resuscitated with acetated Ringer's sodium

Sponsors

Southeast University, China
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years

Inclusion criteria

* Shock patients who need fluid resuscitation with risk factors of acute kidney injury

Exclusion criteria

* Patients with a history of chronic kidney injury and hemodialysis therapy

Design outcomes

Primary

MeasureTime frameDescription
Incidence of acute kidney injury28 dayIncidence of acute kidney injury

Secondary

MeasureTime frameDescription
Application of renal replacement28 dayApplication of renal replacement

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026