Project Baseline Health Study

Conditions

All

Keywords

Baseline, Project Baseline, Baseline Study, Project Baseline Study, Health Study, Baseline Health Study

Brief summary

This study is the first initiative of Project Baseline, a broader effort designed to develop a well-defined reference, or baseline, of good health as well as a rich data platform that may be used to better understand the transition from health to disease and identify additional risk factors for disease. Project Baseline endeavors to test and develop new tools and technologies to collect, organize, and activate health information.

Saman Doroodgar Jorshery, Jay Chandra, Anika S. Walia, Audra Stumiolo, Kristin Corey et al. (21 authors)

The Lancet Digital Health2025-09-011 citations

10.1016/j.landig.2025.100903

Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study

Megan K. Carroll, Sanam Faheem, Jean Bouteiller, Adrian F. Hernandez, Kenneth W. Mahaffey et al. (16 authors)

Frontiers in Digital Health2025-06-24

10.3389/fdgth.2025.1520132

Abnormal Exercise Electrocardiography With Normal Stress Echocardiography Is Associated With Subclinical Coronary Atherosclerosis

Jessica Duran, Peter Shrader, Chuan Hong, François Haddad, Everton J. Santana et al. (16 authors)

Circulation Cardiovascular Imaging2025-01-136 citations

10.1161/circimaging.124.017380

Resting Heart Rate and Associations With Clinical Measures From the Project Baseline Health Study: Observational Study

Kent Y. Feng, Sarah A Short, Sohrab Saeb, Megan K. Carroll, Christoph B. Olivier et al. (13 authors)

Journal of Medical Internet Research2024-10-22

10.2196/60493

Factors associated with lower quarter performance-based balance and strength tests: a cross-sectional analysis from the project baseline health study

Kenneth A. Taylor, Megan K. Carroll, Sarah A Short, Bettia E. Celestin, Adam Gilbertson et al. (8 authors)

Frontiers in Sports and Active Living2024-07-152 citations

10.3389/fspor.2024.1393332

Characterization of peripheral artery disease and associations with traditional risk factors, mobility, and biomarkers in the project baseline health study.

Kercheval JB, Narcisse DI, Nguyen M, Rao SV, Gutierrez JA, Leeper NJ, Maron DJ, Rodriguez F, Hernandez AF, Mahaffey KW, Shah SH, Swaminathan RV, Project Baseline Health Study Group.

2024-07-03

10.1016/j.ahj.2024.06.010

Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy

Best Uchehara, Lydia Coulter Kwee, Jessica A. Regan, Ranee Chatterjee, Julie Eckstrand et al. (17 authors)

Circulation Genomic and Precision Medicine2023-04-1116 citations

10.1161/circgen.122.003772

Multi-dimensional characterization of prediabetes in the Project Baseline Health Study

Ranee Chatterjee, Lydia Coulter Kwee, Neha J. Pagidipati, Lynne Koweek, Priyatham S. Mettu et al. (14 authors)

Cardiovascular Diabetology2022-07-186 citations

10.1186/s12933-022-01565-x

Association of left ventricular diastolic function with coronary artery calcium score: A Project Baseline Health Study

François Haddad, Nicholas Cauwenberghs, Melissa A. Daubert, Yukari Kobayashi, Gerald S. Bloomfield et al. (19 authors)

Journal of cardiovascular computed tomography2022-07-0511 citations

10.1016/j.jcct.2022.06.003

Biological and clinical correlates of the patient health questionnaire-9: exploratory cross-sectional analyses of the baseline health study

Robert M. Califf, Celeste Wong, P. Murali Doraiswamy, David S. Hong, David P. Miller et al. (6 authors)

BMJ Open2022-01-019 citations

10.1136/bmjopen-2021-054741

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Age ≥ 18 * U.S. Resident * Able to speak and read English * Willing and able to comply with all aspects of the protocol

Exclusion criteria

* Individuals working on Project Baseline, including the Baseline Study * Known severe allergy to nickel or metal jewelry

Design outcomes

Primary

Measure	Time frame
Develop a set of scalable and standardized tools for acquiring, organizing, and analyzing clinical, molecular, imaging, sensor, self-reported, behavioral, environmental, and other health-related measurements	For the duration of the study
Evaluate the use of sensor technologies for the collection of continuous, accurate health information	For the duration of the study
Create a dataset encompassing a wide spectrum of phenotypic measures for future exploratory analysis	For the duration of the study
Measure the phenotypic diversity observed among a participant population, defining a range of expected values for multiple types of data	For the duration of the study
Identify biomarkers of disease-related transitions, including those related to cardiovascular disease and cancer	For the duration of the study

Countries

United States

Outcome results