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CAN008 Biomarker CD95 Ligand and CpG2 Methylation in Chinese Patients With Glioblastoma

The Exploratory Study on CAN008 Biomarker CD95 Ligand and Its Promoter (CpG2) Methylation in Chinese Patients With Glioblastoma

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03152708
Enrollment
62
Registered
2017-05-15
Start date
2017-11-01
Completion date
2017-12-31
Last updated
2017-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma

Brief summary

This study was conducted on the post-operative tumor tissues from 62 GBM patients. 20 slices are necessary for all the CD95 and CpG2 test in the central lab by the methods of immunisation and DNA methylation.

Interventions

None listed

Sponsors

CANbridge Life Sciences Ltd.
Lead SponsorINDUSTRY

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Chinese nationality * No limits on Gender and age * First diagnosed GBM * Brain tumor tissue cytological diagnosis of glioblastoma (GBM, pleomorphic glioblastoma, WHO level IV)

Exclusion criteria

* Other types of glioma by histological diagnosis * Tumor tissue not eligible for the central laboratory testing standard * No enough tumor tissue for the central laboratory test

Design outcomes

Primary

MeasureTime frame
CD95 Ligand Positive Rate0 day

Secondary

MeasureTime frame
CpG2 Positive Rate0 day

Contacts

Primary ContactJack Hou
jhou@canbridgepharma.com00862152996609

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026