Blood Loss, Inflammatory Response, Lung Cancer, Postoperative Pain
Conditions
Keywords
thoracoscopic surgery, RATS, VATS, Robot
Brief summary
In this study the investigator will compare the effectiveness of robot assisted thoracic surgery (RATS) with video assisted thoracic surgery (VATS) in case of lung cancer. The perioperative circumstances and postoperative outcome will be compared.
Detailed description
Participants are randomly subdivided (1:1) to either undergo robot assisted lobectomy or video assisted thoracoscopic lobectomy in case of lung cancer. At the end of both surgical interventions the anaesthesiologist administers the same technique of pain relief: paravertebral blockage. The data that are going to be investigated are: operative time, conversion to spreading of the ribs/thoracotomy, blood loss, lymph node dissection, prolonged air leak, chest tube drainage, length of stay, inflammatory reaction (through inflammatory parameters CRP, IL-3, IL-6, TNF), lung recuperation (through a lung function test) and postoperative pain (VAS score questionnaire).
Interventions
PROCEDURERobot assited thoracic surgery
The lobectomy will be preformed in case of an operable lung cancer. The thoracic surgery technique used is robot assisted thoracic surgery
PROCEDUREVideo assited thoracic surgery
The lobectomy will be preformed in case of an operable lung cancer. The thoracic surgery technique used is video assisted thoracic surgery.
Sponsors
Universitair Ziekenhuis Brussel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients must be 18 years old or older * Patients can be male or female * Patients with a lung tumour which is treatable with surgery
Exclusion criteria
* Pregnancy * Inoperable lung tumour * Patients which are at risk for general anaesthesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | 2 months | 0 = no pain 10 = unbearable pain: VASscore |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| operative time | up to 4 hours | duration of surgery |
| conversion to spreading of the ribs/thoracotomy | up to 4 hours | 0 = no 1 = yes |
| lymph node dissection | up to 4 hours | number of lymph nodes |
| prolonged air leak | up to 7 days | chest tube present longer than usual |
| blood loss | up to 4 hours | ml |
| length of stay | up to 7 days | duration of hospitalisation after surgery |
| pulmonary function | 2 months | recovery of function of the operated lung |
| Inflammatory reaction | 48 hours | these inflammatory parameters will be determined: C-reactive protein; IL-3; IL-6; TNF |
| chest tube drainage | up to 7 days | ml |
Countries
Belgium
Contacts
Primary ContactVeerle Van Mossevelde, data nurse
Backup ContactDirk De Clippeleir, data nurse
Outcome results
None listed