Apparently Healthy People Aged 55 and Over
Conditions
Brief summary
Quality of life (QoL) is an important factor for successful aging. Telomere length is an indicator of cellular aging and cumulative biological stress and is thus related to health status and survival. However, the relationship between QoL and telomere length has not yet been examined. In this study we investigated the relationship between leukocyte telomere length (LTL) and QoL. However, the relationship between overall QoL and LTL has not previously been investigated. Therefore, this study was conducted to examine the relationship between LTL and QoL. QoL was measured by the Korean version of the 36-item short-form health survey (SF-36), which is a multidimensional scale consisting of subjective evaluation.
Interventions
OTHERquality of life
Quality of life which was measured by the Korean version of the 36-item short-form health survey (SF-36)
Sponsors
Jung-Ha Kim
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* married couple * apparently healthy subjects above 55 years
Exclusion criteria
* Subjects who had experienced hormone therapy * Subjects who had been diagnosed with dementia, Parkinson's disease, stroke, ischemic heart disease, congestive heart failure, arrhythmia, depression, cancer, thyroid disorders, or chronic renal disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| leukocyte telomere length | 8months | Leukocyte telomere length was measured as telomere repeat copy number relative to single gene copy number by quantitative real-time PCR |
Outcome results
None listed