MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients

Effect of Long and Short Radiotherapy on MMP-7 Levels in Rectal Cancer Treatment

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03151759

Acronym

MMP-7

Enrollment

Registered

2017-05-12

Start date

2002-11-06

Completion date

2007-03-16

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Brief summary

To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.

Interventions

RADIATIONNeoadjuvant radiotherapy

Neoadjuvant radiotherapy prior to rectal cancer surgery

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

Adenocarcinoma of the rectum, ability to understand written and oral information, written consent.

Exclusion criteria

Colon cancer, benign tumors, impaired general condition of patient, declining to participate in the study, synchronous colonic tumors, logistical reasons, inability to understand written and/or oral information, previous pelvic irradiation, ongoing immunosuppressive therapy, diabetes with systemic complications.

Design outcomes

Primary

Measure	Time frame	Description
Matrilysin levels	1 - 6 weeks	Inflammatory markers

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026