Brain-to-Society Diagnostic for Prevention of Childhood Obesity and Chronic Disease

Foundational Work for a Brain-to-Society Diagnostic for Prevention of Childhood Obesity and Its Chronic Diseases Consequences

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03151694

Enrollment

1224

Registered

2017-05-12

Start date

2011-02-01

Completion date

2019-01-31

Last updated

2017-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

childhood obesity, body weight, nutritional risk

Brief summary

This multi-national program applies a breakthrough approach to childhood obesity called, Brain-to-Society (BtS) Diagnostic Approach. In Montreal, Canada and Palwal, India, the investigators will recruit two cohorts of 612 children (6 to 12 years; 306 boy/306 girls) where Whole-of-Society (WoS) transformations are taking place (industrialized societal context with peaking childhood obesity and where a broad governmental plan to promote healthy lifestyle has been adopted -Canada; developing societal context with increasing childhood obesity if replication of past pathways that have lead to double burden; India) are taking place along with World Health Assembly (WHA) resolution A63-12 for marketing of food to children. Individual-level BtS Diagnostic will examine the degree to which individual differences in genetics and biology and differences in the environmental exposures modulate the behavioral, body weight/fatness and nutritional risk over time in the context of WoS transformations. Societal-level BtS Diagnostic shall examine the influence of decisions in policy, investment, business and innovation made by different stakeholders (government, private sector, civil society in health and non-health society systems including agriculture, business and media practices) on the community.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

6 Years to 12 Years

Healthy volunteers

Yes

Inclusion criteria

* Sample population that are exposed to multi-level Whole-of-Society transformation (i.e., Quebec Governmental Action Plan (PAG) and World Health Assembly (WHA) resolution for Quebec sample; Intense Urbanization and Industrialization (IUI) and WHA resolution in India).

Exclusion criteria

* first cousin relations were excluded from the sample population.

Design outcomes

Primary

Measure	Time frame	Description
Individual-level BtS Diagnostic 1	2 years	Genotyping and detection of the Taq1A allele in the dopamine-2 receptor (DRD2) gene.
Individual-level BtS Diagnostic 2	2 years	Genotyping and detection of the exon 3 7-repeat allele of the dopamine-4 receptor (DRD4) gene.

Secondary

Measure	Time frame	Description
Behavioral Assessment	2 years	Assess behavior of each participant in relation to food choice
Body Weight Assessment	2 years	Assess body weight of each participant
Nutritional Risk Assessment	2 years	Assess nutrition intake for each participant.

Countries

Canada, India

Outcome results