Periprosthetic Bone Mineral Density Changes After Implantation Of A Short Hip Stem Compared To A Straight Stem

Periprosthetic Bone Mineral Density Changes After Implantation Of A Short Hip Stem Compared To A Straight Stem: Five-Year Results Of A Prospective, Randomized DEXA-Analysis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03147131

Enrollment

126

Registered

2017-05-10

Start date

2010-08-01

Completion date

2017-07-31

Last updated

2017-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Hip

Keywords

Total Hip Arthroplasty, Short Stem, DEXA

Brief summary

The aim of this study is to evaluate periprosthetic bone mineral density (BMD) changes in the proximal femur after implantation of the Fitmore compared to the CLS stem.

Detailed description

After power analysis, 140 consecutive patients were prospectively included in the randomisation protocol receiving either a Fitmore short or a CLS straight stem. The short stem was assigned in 57 (37% females) cases and the straight stem in 83 (38% females) hips. Periprosthetic bone mineral density was measured before surgery, 7 days, 3, 12 and 60 months postoperatively, using dual energy x-ray absorptiometry (DEXA). The results of the first postoperative measurement served as the baseline value. Because of the different length of the two prostheses we used adapted Gruen zones to divide the periprosthetic bone in seven regions of interest (ROI) with equal length in the proximal zones 1,2,6 and 7, only the regions 3 and 5 featured different sizes. Clinical results were recorded using the WOMAC and the Harris hip score (HHS).

Interventions

PROCEDURETotal Hip Arthroplasty

Total hip arthroplasty was randomly performed wither either a Fitmore short or a CLS straight stem.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Primary or secondary osteoarthritis of the hip * written informed consent * indication for cementless total hip arthroplasty

Exclusion criteria

* previous surgery in the same hip * femoral fracture * metabolic bone disease * drugs affecting bone quality * contralateral THA within the study period * infectious disease or bony tumor

Design outcomes

Primary

Measure	Time frame	Description
Stem specific stress shielding of a short compared to a straight hip stem	Five years postoperatively	Periprosthetic Bone Mineral Density changes around a total hip arthroplasty stem

Secondary

Measure	Time frame	Description
Clinical Outcome after short compared to straight stem THA	Five years postoperatively	Clinical outcome measured with the Harris Hip Score and the WOMAC

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026