Recovery From Anesthesia After Robotic Assisted Radical Cystectomy

Recovery From Anesthesia After Robotic Assisted Radical Cystectomy. Two Different Reversal of Neuromuscular Blockade

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03144453

Enrollment

Registered

2017-05-08

Start date

2017-05-02

Completion date

2019-12-31

Last updated

2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesiology Management

Keywords

Curare, Robotic surgery

Brief summary

Robot-assisted radical cystectomy (RARC) requires specific surgical conditions: steep Trendelenburg position, prolonged pneumoperitoneum, effective neuromuscular block until the final stages of surgery. The aim of this study was to evaluate the quality of awakening in two groups of patients undergoing different combinations of curarization/reversal.

Interventions

DRUGSugammadex Injectable Product

Patients receive sugammadex at the end of the surgery

DRUGNeostigmine, Atropine

Patients receive neostigmine+atropine at the end of the surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* ASA (american society of anesthesiologists) score ≤ III * Patients underwent robotic assisted cystectomy

Exclusion criteria

* Cerebrovascular disease * BMI (body mass index) ≥ 30

Design outcomes

Primary

Measure	Time frame	Description
Time to discharge from recovery room	Up to 240 Minutes After recovery	Time between reversal administration and discharge from the recovery room

Countries

Italy

Contacts

Primary ContactEster Forastiere, Chief

ester.forastiere@ifo.gov.it+39 06 52662449

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026