Cognitive Change, Visual Impairment
Conditions
Brief summary
This study will train participants (young people and older adults) to do a visual task, and will assess whether this results in changes in behavioral assessments. In some participants, we will be also testing whether MRI measures (cortical thickness, functional connectivity) change with training.
Interventions
Computerized training
Sponsors
University of Alabama at Birmingham
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Masking description
Computerized training for all groups. This is a pilot study.
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Healthy volunteers
Yes
Inclusion criteria
* Right handed individuals * Aged 19-89 * In good health as self-reported or visual impairments due to partial vision loss * Normal or corrected-to-normal vision with contact lenses or visual impairments due to partial vision loss
Exclusion criteria
* Younger than 18 or older than 89 * Being hearing-impaired * Not in good health except due to partial vision loss * Having a previous serious head injury or neurological disorder, or loss of consciousness for more than 2 minutes * Having hallucinations or delusions * Having a current or past history of a substance abuse disorder * Currently taking psychoactive medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| scores on acuity tests | baseline | scores on acuity tests |
| scores on spatial attention tests | baseline | scores on spatial attention tests |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in cortical thickness | baseline and immediately following training | Increases in cortical thickness in areas corresponding to trained visual field |
| Changes in functional connectivity | baseline and immediately following training | Changes in functional connectivity of areas corresponding to trained visual field |
Countries
United States
Outcome results
None listed