Rheumatoid Arthritis, Inflammatory Arthritis
Conditions
Keywords
Exercise, Sleep
Brief summary
Regular physical activity is important for people with rheumatoid arthritis (RA). Sleep requirements for adults should be on a 'sleep needs spectrum' of between 7 to 9 hours per day. Poor sleep is a common complaint among people with RA, which may have an effect on their activity levels and well-being. There is evidence that physical activity and exercise can improve sleep quality and disturbances in other chronic disease populations therefore, examining how same affects sleep in RA is important.
Detailed description
Sleep is an important aspect in maintaining the body's circadian rhythm. In general getting fewer than 5 hours sleep per day has been associated with cardiovascular problems, diabetes and obesity and can also be linked to depression and anxiety. Poor sleep is a common complaint among people with rheumatoid arthritis (RA) with disturbed sleep and fatigue known to affect up to 70% in this population. Poor sleep quality may contribute to the feelings of pain, fatigue and poor psychological well-being which in turn may further deteriorate functional ability and reduced activity. It is known that exercise improves a person's psychological state which can also be an additional factor in improving or indeed disrupting quality of sleep. Exercise has been identified as an important part of the nonpharmacological management of poor sleep and in improving sleep quality however, people with RA were previously cautioned about undertaking exercise. Therefore, changes in sleep quality during exercise intervention should be evaluated so that society can understand more the potential for long-term changes in overall health status, in people who have RA. Indeed the intensity level of the activity in people with RA may be of additional importance.
Interventions
BEHAVIORALWalking Programme
The programme will be devised using incremental targets for daily walks based on the 6-20 Borg of rating of perceived exertion scale (Borg RPE). They will be instructed that they should be moderately short of breath on exertion i.e. unable to comfortably hold a conversation while walking
Sponsors
University of Limerick
University Hospital of Limerick
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
At baseline assessment demographic information and outcome measures will be collected by a physiotherapist not involved in the intervention and will be blinded to which arm the participant has been allocated to. This will all take place at the Department of Clinical Therapies, University of Limerick.
Intervention model description
Single centre, single blinded pilot randomised controlled trial, comparing an aerobic intermittent exercise training intervention (walking programme) against verbal and written instructions regarding the benefits of exercise in RA.
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Participants will be eligible to participate if they are aged 18-70; have a diagnosis of RA (defined by the American College of Rheumatology 1987 criteria); have poor sleep (Pittsburgh Sleep Quality Index global score \>5); have a low disease score on 28 joints (DAS28) \<3.2; Health Assessment Questionnaire result of \<2.4 and are able to provided informed consent, understand and speak English. All the above will be determined should the person be interested in participating and before any fitness testing will be place.
Exclusion criteria
* Participants will be excluded from the study if they have severe physical disability (HAQ score \> 2.5); are pregnant; participate in regular physical activity in their leisure time (self-reported aerobic exercise \> 5 times per week); have cardiac symptoms corresponding to New York Heart Association (NYHA) functional classification \> 2;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pittsburgh Sleep Quality Index | 8 Weeks | Sleep |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Profile of Moods State | up to 8 weeks | Mood |
| Quick Inventory of Depressive Symptomatology | up to 8 weeks | Depression |
| State Trait Anxiety Inventory | up to 8 weeks | Anxiety |
| Health Assessment disability Index | up to 8 weeks | Functional limitation |
| RA related Pain - visual analog scale (VAS) consisting of a 10cm horizontal line anchored from 0 (no pain) to 10 (worst pain possible). | up to 8 weeks follow up | Pain |
| Rheumatoid Arthritis-Specific Quality of Life Instrument | up to 8 weeks | Quality of Life |
| Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional Questionnaire | up to 8 weeks | Fatigue |
| Exercise Benefits and Barriers Scale | up to 8 weeks | Exercise barriers |
| Disease Activity Score with 28 joints | up to 8 weeks | Disease activity |
Countries
Ireland
Outcome results
None listed