Candida Infection, Peritonitis Infectious
Conditions
Brief summary
Intraabdominal fungal infections with Candida are constantly increasing. Their diagnosis and treatment is difficult. Morbidity and mortality are high. Β-D-Glucan has been proposed as a marker of systemic fungal infection in candidemia. Moreover, its kinetics is associated with therapeutic success. On the other hand, there are no data on intraabdominal infections that are much more frequent. The objective of the study is to evaluate the initial levels of β-D-glucan and its daily kinetics during the treatment of fungal peritonitis in resuscitation compared to a control group with a yeast-free peritonitis.
Interventions
OTHERTo evaluate the initial levels and kinetics of serum β-D-glucan
To evaluate the initial levels and kinetics of serum β-D-glucan during fungal peritonitis compared to a control group of yeast-free peritonitis
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Major Patient (age ≥ 18 years) * Community or associated peritonitis, operated and hospitalized in resuscitation * Affiliation to a social security scheme
Exclusion criteria
* Allergy known to echinocandins * Dying Patient * Limitation of care * Predictable duration of follow-up ≤ 10 days * Transfusion within 3 months * Patient minor, patient under guardianship or curatorship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood determination of serum β-D-glucan kinetics in patients with peritonitis | 28 days | Blood determination of serum β-D-glucan kinetics in patients with peritonitis |
Countries
France
Outcome results
None listed