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Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03140735
Acronym
VOPRABIO
Enrollment
0
Registered
2017-05-04
Start date
2017-07-03
Completion date
2023-06-20
Last updated
2023-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Stenosis, Pulse Wave

Brief summary

Aortic valve pathology is the third most common cardiovascular disease after coronary artery disease and hypertension, which is responsible for severe morbidity and mortality in elderly patients and requires surgical treatment in its most severe form of progression. The purpose of this study is to find a link between arterial stiffness and degenerative aortic stenosis. If this link is established, arterial stiffness may become a medical therapeutic target in order to delay the evolution of the disease.

Interventions

OTHERStudy the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

OTHERControl group without heart disease

Control group without heart disease

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients over 18 years of age, without legal protection (guardianship or curatorship), * Stable hemodynamic status. * Affiliation to a social security scheme

Exclusion criteria

* Hemodynamically unstable patients: Systolic PA \<10 cmHg, rapid peripheral pulse and spinning, mottling, obnubilation, oliguria, sweating, coma * History of significant valvulopathy other than an aortic stenosis, * Pregnancy. * Patient under tutelage or curatelle or deprived of public right.

Design outcomes

Primary

MeasureTime frameDescription
Analysis of echocardiographic measurements of possible differences between average VOP and Sao i in terms of RA severities10 yearsAnalysis of echocardiographic measurements of possible differences between average VOP and Sao i in terms of RA severities

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026