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Altered MAstication Contribute to TMJ PAin

One Habitual Chewing Side May Contribute to Chronic Temporomandibular Joint Disorder Pain

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03139994
Acronym
MAPA
Enrollment
30
Registered
2017-05-04
Start date
2017-05-02
Completion date
2018-10-30
Last updated
2021-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastication Disorder, Temporomandibular Joint Disorders

Keywords

occlusion, pain

Brief summary

The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors. It has been showed an association: a steeper condylar path, flatter lateral anterior guidance, and habitual chewing on the symptomatic side. This finding argues the possibility of causation of some of these characteristics. This double blind longitudinal study aims to assess if the presence of one habitual chewing side could contribute to temporomandibular joint disorders over time. Method. Young adults with no signs or symptoms of TMD will be assessed. Participants with one chewing side (observed and interview); with steeper condylar path and lower lateral guidance angles will be considered consistent one side chewers, and this side will be considered more susceptible to suffer TMD. Mouth opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD.

Interventions

OTHERDiagnostic

OBSERVATIONAL, DIAGNOSTIC PROCEDURES. Young adults with no signs or symptoms of TMD will be assessed. The chewing function, condylar path angles and lateral guidance angles will be recorded. Maximum comfortable and unassisted jaw opening, hemispheric dominance and hemimandibular retrognathia will be considered as secondary pre-specified outcomes. Three-Four years later, both TMJs of each participant presenting signs and/or symptoms will be evaluated according to DC/TMD. Same recordings as baseline will be carried out.

Sponsors

University of Santiago de Compostela
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* healthies * full dentates * normal occlusion * One habitual chewing side

Exclusion criteria

* Severe malocclusion, dental decay, severe periodontal disease. Pains from other origins or Orthodontics are not criteria for exclusion

Design outcomes

Primary

MeasureTime frameDescription
Change of maximal unassited jaw openingBaseline and 3 years follow-upMaximum unassisted jaw opening or interincisal distance (from edge to edge) measured by a Boley gauge. Up 38 in females and up 40 mm in males are considered limited.
Presence or not of symptoms of temporomandibular joint disorders according to DC/TMDAt 3 years follow-upPain-intensity (0-10 VAS scale, Von Korf)

Secondary

MeasureTime frameDescription
Alteration of lateral dental guidance anglesBaseline and 4-years follow-up (end of the study)Angle between Frankfort plane and lateral dental anterior guidance
Change of maximal comfortable jaw openingBaseline and 4-years follow-up (end of the study)Maximum jaw opening or interincisal distance (from edge to edge) measured by a Boley gauge. Up 38 in females and up 40 mm in males are considered limited.
Change of condylar paths angles inclinationBaseline and 3-4-years follow-up (end of the study)Alteration of parasagittal plane Axiography of condyle motion in respect Frankfort horizontal plane
Change of the habitual chewing sideBaseline and 3-4-years follow-up (end of the study)Determining the habitual chewing side by direct observation using chewing gum, First cicle, and subsequent cicles (7 or over of 10 cicles), interview (used one habitual chewing side?: 1, no, alternate; 2, yes, right; 3, yes, left; 4, I don't know) and kinesiography.
Change of lateral deviation during maximal unassisted jaw openingBaseline, 3 years follow-upKiesiography K7

Other

MeasureTime frameDescription
Hemispheric dominance, asuming oposite side to handedness preferenceBaselineEdinburg inventory (Oldfield)
Hemimandibular retrognathiaBaselineInterincisal median midline and Angle Class on each side
Change of Life qualityBaseline, 3 years follow-upSCL-90-R self-administered questionaire

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026