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Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia

Prospective Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia: Multicentre Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03139786
Enrollment
232
Registered
2017-05-04
Start date
2010-09-16
Completion date
2035-04-01
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Valve, Bicuspid

Brief summary

The aortic valve bicuspidia (BVA) is a congenital condition corresponding to the presence of 2 sigmoids instead of 3. This is the most common cardiac congenital anomaly affecting 0.5 to 2% of the population The general rule. BVA may be associated with structural damage to the ascending aorta, which exposes BVA patients to a risk of developing ascending aortic aneurysm and acute aortic accidents. Recent data from the literature have revealed that the natural history of BVA is marked by a possible development towards significant valvulopathy and / or an ascending aortic aneurysm often requiring surgical treatment. However, the natural history of bicuspid disease remains poorly understood and the prognostic factors for progression to severe valvulopathy and / or aneurysmal dilatation of the ascending aorta remain to be determined.

Interventions

OTHERStudy the natural history of bicuspid

Study the natural history of bicuspid

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients examined in the echocardiography laboratory whose objective examination was a bicuspid valve of the aortic valve * Bicuspidia may be formerly known

Exclusion criteria

* Refusal to participate * Patients who had already undergone bicuspid surgery or ascending aorta before being examined at the echocardiography laboratory

Design outcomes

Primary

MeasureTime frameDescription
Analysis of 10 year mortality in cardiac surgery in a patient with bicuspid10 yearsAnalyzing the natural history of Bicuspidia

Countries

France

Contacts

CONTACTChristophe TRIBOUILLOY, PhD
tribouilloy.christophe@chu-amiens.fr+33322455885

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 16, 2026