Wasting in Chronic Kidney Disease

Wasting in Chronic Kidney Disease: Refeeding Techniques and Artificial Nutrition Practices

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03135717

Acronym

PEW

Enrollment

Registered

2017-05-01

Start date

2011-12-31

Completion date

2012-06-30

Last updated

2017-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Hospitalized

Keywords

Chronic kidney disease, Enteral nutrition, Oral nutritional supplements, Parenteral nutrition, Refeeding, Wasting

Brief summary

Protein energy wasting is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of dialysis. It covers 20 to 70% of patients diagnosed with chronic kidney disease according to the degree of evolution of the disease and the diagnostic method. Mechanisms of PEW are based mainly on anorexia and metabolic abnormalities caused by kidney disease. Nutritional treatment differs depending on the stage of the kidney disease acute or chronic treated whether or not by dialysis. Nutritional monitoring should be regular, individualized and collaborative to detect a risk of PEW or treat installed PEW. Refeeding techniques should allow all the nutritional needs. Their indications depend on the clinic, biochemical assessment and nutrient intake.

Interventions

DIETARY_SUPPLEMENTNutritional care

* Diagnosis of protein energy wasting : anthropometry, calculation of the nutrient intakes, evaluation of appetite, evaluation of gastrointestinal syndromes, hand grip test and bioimpedancemetry * Treatment of protein energy wasting : estimation of nutritional requirements, prescription of oral nutritional supplement or artificial nutrition, physical rehabilitation * Multidisciplinary approach (nephrologists, dieticians, physiotherapists, nurses) * Evaluation of the nutritional treatment (plasma albumin and prealbumin, weight evolution, muscle strength and body composition)

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

44 Years to 73 Years

Healthy volunteers

Inclusion criteria

* Patients with kidney disease * Patients hospitalized in a university hospital renal ward

Exclusion criteria

\- Hospitalization less than two weeks

Design outcomes

Primary

Measure	Time frame
Nutritional care evaluated with questionnaire	Since admissions to hospital, up to 4 weeks

Secondary

Measure	Time frame
body composition	Since admissions to hospital, up to 4 weeks
physical activity	Since admissions to hospital, up to 4 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026