Hypertrophy; Scar
Conditions
Keywords
hypertrophy scar, burn
Brief summary
Assess the effect of extracorporeal shock waves on hypertrophy scar
Detailed description
Prolonged and abnormal scarring after trauma, burns and surgical procedures often results in functional and cosmetic deformities. A wide variety of treatments have been advocated for pathologic scars regression. Unfortunately, the reported efficacy has been variable.Unfocused extracorporeal shock wave therapy is a feasible and non-intensive treatment. And it is an emerging option for the treatment of painful and retracting scars. Administration of ESWT appears to result in significant improvements in scar clinical appearance, mobility and subjective pain. Clinical data were mirrored by histologic changes in connective tissue appearance and scar vascularization. Extracorporeal shock wave therapy is also an effective and conservative treatment for patients with aesthetic and functional sequela from burn scars. It is a feasible, cost-effective, well-tolerated treatment that can be used in the management of post-burn pathologic scars after the patients are briefed on the practical aspects of the treatment procedure.
Interventions
DEVICEextracorporeal shock-wave
to treat painful and retracting scars
OTHERmassage
to treat painful and retracting scars
Sponsors
Mackay Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. aged between 18 \ 65 years old; 2. at least 4 weeks since onset of onset of wound; 3. healing wound with at least 6 scores in Modified Vancouver Scar Scale for more than four weeks 4. the most important of all, read and signed the inform concern of this study.
Exclusion criteria
1. patients with open wound; 2. oxygen dependent 3. having evidence of cognitive deficit; 4. having local infection, severe inflammation or otherwise lesion that is not suggestive for ESWT; 5. patient with serious medical problems, as uncontrolled hypertension, coagulopathy, recent severe hemorrhage, neoplasm, severe hepatic disease, epilepsy, cutaneous pathology, mental retardation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change from baseline thick of scar | immediately post intervention, 1 month after, and 3 months | sonography for thick of scar |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change from baseline Modified Vancouver Scar Scale | immediately post intervention, 1 month after, and 3 months | questionnaires of Modified Vancouver Scar Scale for scar measure |
| change from baseline Visual analogue scores (VAS) | immediately post intervention, 1 month after, and 3 months | Visual analogue scores (VAS) for pain |
| change from baseline skin color | immediately post intervention, 1 month after, and 3 months | DermaLab Combo series for skin color |
| change from baseline Patient Scar Assessment Scale (POSAS) | immediately post intervention, 1 month after, and 3 months | questionnaires of Patient Scar Assessment Scale (POSAS) for scar measure |
Countries
Taiwan
Contacts
Primary ContactLi-Ru Chen, MD
Outcome results
None listed