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Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria

Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03133949
Enrollment
210
Registered
2017-04-28
Start date
2010-09-24
Completion date
2021-08-30
Last updated
2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Aortitis, Retroperitoneal Fibrosis

Brief summary

Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological characteristics should make it possible to differentiate them and dismember the Nosological field. This will be an essential first step before studying prognosis, risk factors, and therapeutic options. The search for diagnostic criteria on a large series, similar to the study of classification of vascularites of the ACR in 1990, should make it possible to homogenize the diagnoses for the different teams working on the subject, and to begin work Collaborations, which alone can improve patient care in the future.

Interventions

OTHEREstablish the clinical, biological and radiological characteristics of patients

Establish the clinical, biological and radiological characteristics of patients

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Cases : * All cases of idiopathic aortitis and retroperitoneal fibrosis followed in participating centers over the past 15 years will be collected. * Witnesses : * Group 1: non-idiopathic inflammatory aortitis: all cases of inflammatory aortitis (apart from idiopathic aortites and isolated retroperitoneal fibrosis) followed in the participating centers over the last 15 years will be collected. * Group 2: subjects with noninflammatory aortic disease, atheromatous type or annulo-ectasitic disease, matched by age and sex with cases. This group will be used to define the differential characteristics between idiopathic aortitis and noninflammatory aortic pathology. * Group 3: This group will include control subjects aimed at defining radiological normality criteria according to age and sex. As the images are machine-dependent, group 3 controls will be randomly selected from the radiology departments that have performed the scanner or MRI of the corresponding control.

Exclusion criteria

* Patients under 18 years of age

Design outcomes

Primary

MeasureTime frame
Analyze the management of patients with aortic and retroperitoneal fibrosis1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026