Sedation During Spinal Anesthesia
Conditions
Brief summary
Patients during spinal anesthesia should be sedated.
Detailed description
Spinal anesthesia offers a number of advantages to both the patient and the physician. However, patients are often reluctant to remain awake during a procedure. Sedation has been shown to increase patient satisfaction during regional anesthesia and may be considered as a means to increase the patient's acceptance.Therefore, provision of adequate sedation is important if the advantages of spinal anesthesia are to be fully appreciated.
Interventions
DRUGKetamine
Patient will receive IV ketamine 0.5 mg/kg diluted in normal saline to a volume of 50 ml over 10 min
DRUGMidazolam
Patient will receive IV midazolam 0.03 mg/kg diluted in normal saline to a volume of 50 ml over 10 min
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Male patients aged from 18 to 50 years old undergoing elective unilateral inguinal hernia repair with no neurological, cardiovascular and hepato-renal abnormalities.
Exclusion criteria
* Age: younger than 18 or older than 50. * Psychatric or neurological disorders. * Cardiovascular disorders. * Coagulation disorders. * Contraindications to neuraxial block (allergy to L.A, peripheral neuropathy, prior spine surgery).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time for the onset of sedation in minutes assessed by modified observer's assessment of alertness/sedation score | 90 minutes after spinal anesthesia | assessed by modified observer's assessment of alertness/sedation score |
Countries
Egypt
Outcome results
None listed