Hypopharyngeal Carcinoma, Laryngeal Carcinoma
Conditions
Brief summary
To determine if MRI can detect preoperative invasion of cartilage by laryngeal and hypopharyngeal carcinoma, and to compare it to CT imaging and histopathology in excised larynges and/or hypopharynges.
Interventions
OTHERPharyngo laryngeal MRI
Patients will be outgoing a pharyngolaryngeal MRI, with injection of gadolinium, in addition to the CT imaging. They will have this MRI in case of doubt about cartilage invasion. It will be realised during the time between the CT imaging and the day of surgery. Device : gadolinium-based MRI contrast agent This will be realized according to the standard procedure.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient ≥18 years old * Patient with a laryngeal or hypopharyngeal cancer at any stage * Patient eligible for a surgical treatment in multidisciplinary consultation * Patient who did not oppose its participation to the study * Indication for performing an MRI in addition to CT at the discretion of the investigator
Exclusion criteria
* Patient with an ASA (American Society of Anesthesiologists, international anesthesia classification) score ≥ 3, * Patient with a chirurgical contraindication * Patient with a MRI contraindication * Pregnant or nursing woman * Adult requiring protection (guardianship, supervision) * Patient participating in interventional research (Excluding physiological studies and interventional research involving only minimal risks and constraints that do not interfere with the analysis of the primary outcome).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Endoscopy | 1-4 weeks | Tumor stage and cartilage invasion as determined by endoscopy : invaded/non invaded/undetermined |
| CT scan | 1-4 weeks | Tumor stage and cartilage invasion as determined by CT scan : invaded/non invaded/undetermined |
| MRI | 1-4 weeks | Tumor stage and cartilage invasion as determined by MRI : invaded/non invaded/undetermined |
| Anatomopathological analysis | 2-4 weeks | Tumor stage and cartilage invasion as determined by histopathology in excised pieces : invaded/non invaded/undetermined |
Countries
France
Outcome results
None listed