Colonic Cancer
Conditions
Keywords
Postoperative pain, Postoperative recovery, Intracorporeal anastomosis, Robotic right colectomy
Brief summary
Right-sided colonic cancer is treated with right-sided colectomy, predominantly performed as minimally invasive surgery with extracorporeal anastomosis (ECA). In recent years a new technique with intracorporeal anastomosis (ICA) has emerged and it is thought that ICA is less invasive and thereby has the potential to improve the postoperative course of right colonic cancer patients. The objective of this study is to compare robotic right colectomy with either ICA or ECA in a randomized controlled setting.
Interventions
PROCEDUREIntracorporeal anastomosis
Use of intracorporeal anastomosis technique
PROCEDUREExtracorporeal anastomosis
Use of the conventional extracorporeal anastomosis technique
Sponsors
Herlev and Gentofte Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Intervention model description
Randomized controlled trial
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
All patients scheduled for robotic right colectomy due to colonic cancer are eligible for inclusion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative recovery | 1 month | Questionnaire of Recovery 15 (QoR-15) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to first bowel movement | 1 month | — |
| Length of hospital stay | 1 month | — |
| Morbidity | 1 month | — |
| Mortality | 1 month | — |
| Postoperative pain | 1 month | — |
| Time fo first flatus | 1 month | — |
| Timed up and go-test | 2 days | — |
| Ortostatic hypotension test | 2 days | — |
| Spirometry and PEF - test | 2 days | Postoperative pulmonary function |
| Postoperative opioid usage | 1 month | — |
| Whole blood gene expression profiling | 1 month | Measuring changes in expression of ROS and immulogical genes due to surgery. |
| Heart Rate Variability | 2 days | Continuously ECG-monitoring intraoperatively and postoperatively |
Countries
Denmark
Outcome results
None listed