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Incidence and Risk Factors of Extubation Failure in Pediatric Resuscitation

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03129802
Enrollment
60
Registered
2017-04-26
Start date
2016-07-31
Completion date
2017-08-31
Last updated
2017-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Insufficiency

Keywords

extubation, pediatric resuscitation, reintubation, failures of extubation., Respiratory Insufficiency

Brief summary

The failure of extubation in pediatric resuscitation is most often described as the need for reintubation within 48 hours after extubation. The failure rate of extubation in pediatric intensive care varies in the literature there is 4 to 22% failure. These failures result in increased mortality, morbidity with a use of larger tracheostomy, a prolonged residence time. Some risk factors are well defined in the literature as the duration of intubation, ENT and neurological history, the persistence of a respiratory disease, a high level of sedation. Other factors are more controversial as age, ventilatory parameters just before extubation before extubation blood gases, the interest of a leak test. Also pediatric populations are extremely heterogeneous, so the investigators would like to highlight to extubation failure risk factors in Hautepierre pediatric ICU to better support these high-risk children.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No

Inclusion criteria

* Children hospitalized in pediatric intensive care, under 18 years, intubated, ventilated for more than 2 hours and for which planning extubation or intubated children for whom an unplanned extubation just happened. * Children whose holding parental authority are not opposed to the use of clinical data from their child for research purposes.

Exclusion criteria

* Refusal to participate in the study

Design outcomes

Primary

MeasureTime frame
Failure of extubationneed for a new intubation within the first 48 hours after extubation

Countries

France

Contacts

Primary ContactAnne-Sophie Guilbert, MD
anne-sophie.guilbert@chru-strasbourg.fr33 (0)3 88 12 73 20
Backup ContactLucie PETITDEMANGE
lucie.petitdemange@chru-strasbourg.fr33 (0)3 88 12 73 20

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026