Bone Neoplasm
Conditions
Keywords
allograft, distal tibia sarcoma
Brief summary
The study show the clinical results of limb salvage for primary malignant bone tumor of the distal tibia using block excision of the tumor and reconstruction with allograft arthrodesis with different methods of fixation (plates or intramedullary nail system)
Detailed description
It is well known that before the 1980's the usual treatment for the sarcomas of the distal tibia was amputation (1). Currently, however, after the improvement of the chemotherapy treatments, potential reconstructions of the area in well studied patients are possible, and for that we have a wide range: auto graft, allograft and prosthetic reconstructions (2, 3) Is important to know that osteosarcoma still meant the principal diagnosis, followed by the Ewing sarcoma and synovial sarcoma, but their malignant potency is lower than when they are present in the rest of the body (4, 5, and 6) The purpose of this study is to recollect the patients' data followed from different institutions and countries that have the criteria for their inclusion in the study (primary malignant bone tumor of the distal tibia that underwent block excision of the tumor and reconstruction with allograft arthrodesis from the patient management for any of the multidisciplinary sarcoma team including in this study).
Interventions
PROCEDUREallograft arthrodesis of ankle
patients that underwent trought a block resection of a malignant tumor of the distal tibia and reconstruction with allograft arthrodesis
Sponsors
Hospital del Niño Dr. José Renán Esquivel
Patricia Bonilla
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
\- all patients with histopathologyc diagnosis of a primary malignant bone tumor at the distal tibia that went through a tumor resection and received reconstruction with allograft as first surgical treatment
Exclusion criteria
* none histopatologic proved diagnosis * patients that received other kind of surgical treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| principal diagnosis of the patients that wen trough ankle after resection of a primary malignant tumor of the distal tibia | 1 month | osteosarcoma: 5 patientas (2 females of 18 and 15 years old and 3 males of 19, 24 and 16 years old) telangiectasic osteosarcoma (1 female of 21 years old) Ewing sarcoma (1 male of 33 years old) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| mobility | 5 month to 10 years follow up | surgical site infection, non union, malunion, osteosynthesis material failure |
| mortality | 5 months to 10 years follow up | secundary of the primary tumor diagnosis or metastatic disease of it |
| MSTS SCORE | 5 month to 10 years follow up | total points score of the msts score at the final follow up |
Countries
Panama
Contacts
Primary Contactpatricia bonilla, MD
Backup ContactJorge Navia, MD
Outcome results
None listed