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Comparison of Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position

Comparison of Extent of Epidurography and Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03128788
Enrollment
30
Registered
2017-04-25
Start date
2017-03-02
Completion date
2018-02-02
Last updated
2018-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Epidural Injection

Keywords

epidurography epidural pressure patient posture

Brief summary

It is reported that the distribution of contrast medium had an obvious correlation with the extent of sensory analgesia after injection of LA. Our previous study showed that different posture (prone vs. lateral decubitus) resulted in different degree of contrast medium spread. We supposed that differences of epidural pressure between diverse postures might be one factor contributing those differences of epidurography. This study was designed to compare the epidural pressure and extent of spread of epidurography between prone and lateral decubitus position

Detailed description

It is known that postoperative pain after thoracotomy or lobectomy is very severe, therefore, intraoperative or postoperative pain management using continuous thoracic epidural catheterization is suggested good option to prevent this potential complication. The spread of local anesthetics is influenced by various factors including volume, location of needle insertion, speed of injection, patient position, age, weight and height. However, there are few studies about the effect of different patient position affeting the epidural pressure and the extent of spread of contrast medium during thoracic epidural catheterization. Studies of lumbar epidural blockade have shown that lateral position can produce 0-3 segment more to the dependent position compared to the supine position. When the same amount of local anesthetic was injected in supine of sitting position, the most cephalad level of spread was indifferent. Recent studies showed that neck flexion demonstrated significant cephalad spread of contrast dye in high thoracic epidural blockade. The purpose of this study was to compare and evaluate the changes of epidural pressure with extent of spread of contrast medium between different posture

Interventions

thoracic epidural catheterization thoracic epidural catheterization for the management of postoperative pain

Sponsors

Keimyung University Dongsan Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* lung cancer * liver cancer * stomach cancer * pancreas cancer

Exclusion criteria

* coagulopathy * infection * previous spine fusion at thoracic level

Design outcomes

Primary

MeasureTime frameDescription
Epidural pressure15 minutes after the completion of the interventionEpidural pressure (mmHg) measurement using pressure transducer between different posture

Secondary

MeasureTime frameDescription
Contrast dye assessment5 minutes after the completion of the interventionNumber of segment convered by contrast dye assessed through fluoroscopic image

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026