Effects of Essence of Chicken on Physical Fatigue, Working Memory and Attention

Effects of the Supplementation of Essence of Chicken on Physical Fatigue and Brain Functions Such as Working Memory and Attention Among Healthy Adults

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03128476

Enrollment

364

Registered

2017-04-25

Start date

2016-03-03

Completion date

2017-01-30

Last updated

2017-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue, Healthy Subjects

Brief summary

In Southeast Asia, Essence of Chicken, a chicken-meat-extract, is a popular beverage and is consumed as a traditional remedy for several ailments, including the use as a nutritional supplement for sickness, enhancement of mental efficiency, and recovery from mental fatigue. While the elderly use it as a nutritional supplement, students use it for relief from anxiety during exam times. The present study is conducted in order to assess the effects of BEC on various physical and mental parameters including physical fatigue, working memory and attention, mood and stress, in comparison to placebo.

Interventions

DIETARY_SUPPLEMENTEssence of Chicken

Brand's Essence of Chicken (BEC) is produced via a water extraction process from chicken meat for several hours under high-temperature, followed by centrifugation to remove fat and cholesterol, vacuum concentration to 3- to 4-fold, sterilization by high temperature and pressure before bottling. This kind of chicken essence is rich in protein, and low in sugar and fat, conveniently available and consumable, and easy for household storage.

DIETARY_SUPPLEMENTPlacebo (Energy matched)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Normal BMI * Not continuously taken Essence of Chicken for the last 3 months * Physical and psychological fatigue inclusion criteria/test/cutoff using CFQ (where individuals' CFQ scores 4 or above)

Exclusion criteria

* Suffering from chronic or malignant diseases e.g. cancer, heart, liver, renal or other metabolic diseases. * Any psychiatric or neurological disease * Pregnant and lactating women * Subjects participated in any investigational drug trial within 4 weeks before screening * Consumption of food supplement in the previous 2 weeks * Professional athletes * Subjects with recent lifestyle changes in the past 4 weeks * History of allergy to chicken meat and seafood

Design outcomes

Primary

Measure	Time frame	Description
Working memory	4 weeks	Digit Span test (Maximal FORWARD digit span and Maximal BACKWARD digit span, etc)
Fatigue-vitality	4 weeks	Psychometric tests SF-36 (score 100%)
Physical fatigue	4 weeks	Chalder Fatigue Questionnaire (score 0-33)
Attention	4 weeks	Stroop (mean latency and proportion correct)
Sustained attention	4 weeks	Sustained Attention to Response Task (mean latency and % of correct trials)

Secondary

Measure	Time frame	Description
Stress	4 weeks	DASS is used as a psychometric test to measure stress (score 0-42).
Adverse effects	4 weeks	Comparison of adverse events on IP and placebo groups.
Mood	4 weeks	POMS brief is used as a psychometric test to measure mood (6 domains).

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026