Further Psychometric Data for the Reliability and the Diagnostic Validity of CRS-R

Further Psychometric Data for the Reliability and the Diagnostic Validity of the Coma Recovery Scale-Revised

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03126929

Enrollment

169

Registered

2017-04-25

Start date

2012-03-31

Completion date

2017-03-31

Last updated

2017-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minimally Conscious State, Vegetative State

Keywords

disorders of consciousness, Vegetative state, Minimally conscious state, Emergence from MCS, Coma Recovery Scale-Revised

Brief summary

This study aims to provide, in a large sample, further psychometric data as regards the internal consistency, the test-retest reliability and the diagnostic validity of the Coma Recovery Scale-Revised (CRS-R).

Detailed description

Recently, a report of the American Congress of Rehabilitation Medicine aiming to provide a systematic review of behavioral assessment scales for DOC has indicated that, when compared to other scales, the CRS-R meets the highest psychometric standards for the evaluation of severely brain-injured patients and may be used to assess DOC with minor reservations. However, that report mentions few evidences or studies with small sample sizes for some aspects of its reliability and validity such as its internal consistency and its test-retest reliability.The report also states that the diagnostic validity of the CRS-R remains unproven. In this study, the investigators will therefore aim to provide further psychometric data as regards those variables in a large sample of patients with DOC

Interventions

DIAGNOSTIC_TESTComa Recovery Scale-Revised and Glasgow Coma Scale

Patients have been assessed with both the Coma Recovery Scale-Revised(CRS-R) and the Glasgow Coma Scale(GCS)

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 86 Years

Healthy volunteers

Inclusion criteria

* age above 18 years old * any etiology * pre-screening performed by the referent physician comforting the presence of a disorder of consciousness in accordance with international diagnostic criteria for VS, MCS or emergence from MCS (EMCS)

Exclusion criteria

* neuromuscular blocking agents or sedative drugs administered within the prior 24 hours * no documented history of a prior coma * critical illness or unstable medical condition

Design outcomes

Primary

Measure	Time frame	Description
Coma Recovery Scale-Revised for assess the level of consciousness	24 hours(1 day)	Rater Measured the score of Coma Recovery Scale-Revised(CRS-R) within 24h. The CRS-R consists of 23 items grouped in six subscales addressing auditory, visual, motor, oromotor, communication and arousal functions. The lowest item on each subscale represents reflexive activity while the highest items represent cognitively-mediated behaviors.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026