End Stage Renal Disease
Conditions
Keywords
Exercise, Hemodialysis, Virtual Reality
Brief summary
All participants exercised during 16 weeks following a conventional intradialysis exercise program. The last 4 weeks of the study participants were randomized into two different exercise programs intradialysis. One group exercised through a virtual reality exercise adapted specially for patients while receiving hemodialysis treatment. The other group exercised with a conventional exercise program, combining aerobic cycling and strengthening exercises.
Detailed description
The first 16 weeks all participants followed an intradialysis exercise program. The exercise program consisted of strengthening exercises for lower limbs and for the upper limb free of fistula. The exercise program included isotonic exercises for quadriceps, triceps surae, psoas, glutei, and brachial biceps; and isometric exercises for hip adductors and hamstrings. Elastic bands were used to apply resistance. Progression was achieved from increasing from 1 set of 10 repetitions until 3 sets of 15 repetitions. This first part lasted no more than 30 minutes. The program also included aerobic exercise (cycling) for up to 30 minutes. Intensity was adapted through the duration of the study so that the participant felt the exercise from hard to somewhat hard (13 to 15 at the rate of perceived exertion 6 to 20). Time and resistance were adapted progressively. The last four weeks of the program participants were randomized into virtual reality exercise or conventional exercise group. The virtual reality exercise group undertook 30 minutes of exercise. After warming up, participants had to play to an adapted 'treasure hunt' game. Their legs movements were the players projected into an individual tv that gave them feedback regarding their achievements. The aim of the game was to achieve the higher possible score.They moved to pick up coins and to avoid bombs. An adapted Kinect technology was used for the game development.
Interventions
Game developed by the Kinect, adapted to the lying position of participants.
OTHERConventional exercise intradialysis
Aerobic exercise (cycling) and strengthening exercise for lower limbs using elastic bands and gravity
Sponsors
Hospital de Manises, Valencia
Cardenal Herrera University
Study design
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Patients in HD therapy at least 3 months
Exclusion criteria
* recent myocardial infarction (within 6 weeks) * unstable angina * malignant arrhythmias * above the knee amputation without replacement * cerebral vascular disease (ictus, transient ischemia) * musculoskeletal and respiratory disorders that can get worse with exercise * impossibility to achieve functional testing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sit to Stand to Sit test 10 | 20 weeks | Time required to stand up from a chair and sit down 10 consecutive times |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Short Physical Performance Battery | 20 weeks | Balance, gait speed and sit to stand to sit 5 times |
| One leg stand test | 20 weeks | Time to keep balance on one leg |
| Sit to Stand to Sit test 60 seconds | 20 weeks | Number of repetitions achieved of standing up from a chair during 60 seconds |
| Handgrip | 20 weeks | Handgrip strength right and left hands |
| One leg heel rise test | 20 weeks | Number of repetitions of standing on toes in both legs |
| Timed Up and Go | 20 weeks | Time to stand up, walk a short distance, turn, walk back and sit down to the chair again |
| Adherence | 20 weeks | Sessions performed/offered |
| Physical Activity | 16 weeks | Human activity profile, adjusted and maximal activity score |
| Inflammatory markers | 16 weeks | Interleukin 6 (IL6) |
| Health-related quality of life | 16 weeks | SF-36 subscales and components |
| Oxidative stress markers | 16 weeks | Malondialdehyde (MDA) |
| 6 minutes walk test | 20 weeks | Number of meters covered during 6 minutes of walking |
Countries
Spain
Outcome results
None listed