Iodine Status in Pregnant Women in Israel

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03120221

Enrollment

160

Registered

2017-04-19

Start date

2017-07-04

Completion date

2018-12-31

Last updated

2018-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iodine-Deficiency; Hypothyroidism

Keywords

Pregnancy, Iodine deficiency, Thyroid

Brief summary

Worldwide Data suggest that Iodine deficiency is a concern among healthy pregnant women. Thus, screening first trimester healthy pregnant women for iodine status is of clinical value for mother and child as iodine deficiency might have implications on thyroid function as well as pregnancy outcomes

Detailed description

New emerging data suggest pregnant women in Israel are iodine deficient in the first trimester of pregnancy. This is of major concern as first trimester iodine sufficiency is critical for the development of the fetal brain. Our aim is to evaluate iodine consumption in first trimester pregnant women in Israel through dietary questioners, Urinary iodine samples and thyroid functions test assessed through blood samples. All data will be analyzed in a central lab.

Interventions

DIAGNOSTIC_TESTUrine sample for iodine measurement

Women will be required to give a urine sample for iodine measurement

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

First trimester pregnant women with a singleton pregnancy

Exclusion criteria

1. Women with a known thyroid disease treated or untreated 2. Women who received contrast material in the year previous to the study 3. women with any chronic disease 4. Women who receive chronic medication not including vitamins

Design outcomes

Primary

Measure	Time frame	Description
Evaluation of average iodine consumption in food	1 year	Iodine consumption will be evaluated trough detailed food questionnaires. Data will be quantified and reported in micrograms per day
Evaluation of urinary iodine concentration	1 year	Women will give a spot urine sample for urinary iodine concentration measurement. All data will be analyzed and reported in micrograms/L. Data obtained will be compared to World Health Organization requirements
Thyroid function test measurement	1 year	Thyroid function will be evaluated through blood tests in the first trimester of pregnancy. Data will be analyzed in accordance with local guidelines.

Countries

Israel

Contacts

Primary ContactTal Schiller, MD

talsc1@clalit.org.il972-8-9441315

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026