Postoperative Complications After Appendectomy

Clinical Value of Postoperative C-reactive Protein in the Detection of Complications After Open and Laparoscopic Appendectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03119740

Enrollment

744

Registered

2017-04-19

Start date

2016-08-01

Completion date

2016-11-30

Last updated

2023-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appendicitis

Brief summary

The frequency of complications after appendectomy is about 9% . The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Detailed description

Background: Acute appendicitis is a common emergency in general surgery. The frequency of complications after appendectomy is about 9% \[9\]. The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications. Methods: This retrospective single-center cohort study comprised 744 patients who had undergone open or laparoscopic appendectomy for clinically suspected appendicitis between 1 January 2011 and 31 December 2015 at the department of general and visceral surgery, Kepler University Hospital in Linz, Austria. Demographic data, the surgical technique, postoperative complications, histopathological findings, postoperative white blood counts, and C-reactive protein levels were evaluated.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 96 Years

Inclusion criteria

* clinically suspected appendicitis between 1 January 2011 and 31 December 2015

Exclusion criteria

* an elective appendectomy as part of an oncological or gynecological operation tumor was found intraoperatively and required ileocecal resection or right hemicolectomy

Design outcomes

Primary

Measure	Time frame	Description
superficial wound infection	4 weeks postoperative	superficial wound infection in open and laparoscopic appendectomy

Secondary

Measure	Time frame	Description
intraabdominal abscess	4 weeks postoperative	intraabdominal abscess in open and laparoscopic appendectomy
ileus	4 weeks postoperative	ileus in open and laparoscopic appendectomy

Countries

Austria

Outcome results