Colorectal Polyp
Conditions
Brief summary
To assess the accuracy of predicting histology of colorectal polyps with electronic chromoendoscopy.
Interventions
DIAGNOSTIC_TESTPrediction of Histology
The accuracy of predicting the histology of colorectal polyps will be assessed with HD-WLE and EC
Sponsors
University of Erlangen-Nürnberg Medical School
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* patients undergoing screening or surveillance colonoscopy * written informed consent
Exclusion criteria
* inadequate bowel preparation * polyposis syndromes * history of colectomy * use of anticoagulants
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of predicting histology with EC | 1 year | Polyps will be visualized in white-light and the location and size will be noted. Afterwards, electronic chromoendoscopy will be used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist will then make a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, a level of confidence (high or low) will be made for the real time histology prediction. Finally, all polyps will be removed using standard techniques and processed for pathological evaluation and real time and histological results will be compared. |
Countries
Germany
Outcome results
None listed