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Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03117491
Enrollment
150
Registered
2017-04-18
Start date
2015-12-01
Completion date
2016-12-01
Last updated
2017-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic Irreversible Pulpitis

Keywords

Gow-Gates nerve block, Inferior alveolar nerve block, local anesthesia, molar, pulpitis

Brief summary

Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Detailed description

Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis. Methods: One hundred fifty subjects with irreversible pulpitis of a mandibular molar were selected. subjects randomly received two IANB injections or two GGNB injections or their combination of 1.8 mL 2% lidocaine with 1:100,000 epinephrine. Success was specified as no or mild pain on the basis of Heft-Parker visual analogue scale recordings up on the access cavity preparation or initial instrumentation. Data were analyzed by Kruskal-Wallis, and ANOVA tests.

Interventions

PROCEDUREGGNB injections

The patients received two GGNB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine

PROCEDUREIANB injections

The patients received two IANB injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine

PROCEDUREGGNB + IANB injections

The patients received one GGNB injection plus one IANB injection of 1.8 mL 2% lidocaine with 1:100,000 epinephrine

Sponsors

Isfahan University of Medical Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* vital mandibular molar tooth * diagnosis of symptomatic irreversible pulpitis

Exclusion criteria

* younger than 18 years old * history of significant medical conditions * allergies to local anesthetics or sulfites * pregnancy * taking any medications that might influence anesthetic assessment * active sites of pathosis in area of injection * inability to give informed consent

Design outcomes

Primary

MeasureTime frame
the success rate of GGNB local anesthesia technique based on Heft-Parker visual analog scaleat time of access cavity preparation
the success rate of IANB local anesthesia technique based on Heft-Parker visual analog scaleat time of access cavity preparation
the success rate of GGNB + IANB local anesthesia techniques based on Heft-Parker visual analog scaleat time of access cavity preparation

Secondary

MeasureTime frame
initial pain based on Heft-Parker visual analog scalebefore treatment

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026