Skip to content

Altruistic Decisions

Study on the Parameters That Influence Perceptual Decisions

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03116581
Enrollment
159
Registered
2017-04-17
Start date
2014-02-03
Completion date
2016-07-22
Last updated
2017-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Perceptual Decision, Social Cognition, Motivation

Brief summary

The study aimed to understand how payoffs for others influence perceptual decision making. The research consists in testing how varying monetary payoffs for another modify the perceptual decision making processes. The use of drift diffusion models on a random dots task enable the characterization of the decision parameter(s) that are modulated when a decision is made to win payoffs for others as compared to decisions for self-benefits. Once the parameter revealed through behavioral experiment, neuroimaging is applied to find the neural correlates of the effects of taking others into account in the decision making process.

Interventions

OTHERBehavior

Random-dots tasks: dots appear and move, most have a random trajectory but a given proportion of them move coherently to the same direction. * Vicarious reward Each trial begins with a cue, showing 'me' or 'him' and filled rectangle filled proportionally to the payoff. The cue and the square are depicted in yellow (oneself) or blue (other), depending on the beneficiary. The moving dots are then presented and the subjects respond. At the end of dots motion, the feedback is presented. If the response was correct, a pile of coins proportional to the payoff is shown. For incorrect responses and misses, a red-colored cross is displayed. * Audience effect Each trial begins with the display of two eyes (public) or a padlock (private). The moving dots are shown and the participant answers. Audience condition changes the information available on accuracy when submitting comments. In the observed condition, an arrow shows the response. In the observed condition, no feedback is displayed.

OTHERfMRI (functional Magnetic Resonance Imagery)

Both behavioral task (audience effect and vicarious reward) will be studied in fMRI (functional Magnetic Resonance Imagery). The same paradigms used in the behavioral experiment will be adapted for fMRI. Audience Effect experiment: trials will last for 10 seconds maximum. With 80 trials for each condition (public easy, public difficult, private easy and private difficult), the task will count a total of 320 trials and have a 54 minutes duration, in 3 runs of 17 minutes each. Vicarious Reward experiment: trials will have a 10 seconds maximum duration. Using 40 trials for each condition (other low payoff, other high payoff, self low payoff, self high payoff, control condition), the task will have a total of 200 trials and last for 54 minutes, in 6 runs of 9 minutes each.

Both behavioral task (audience effect and vicarious reward) will be studied in MEG (MagnetoEncephaloGraphy). The same paradigms used in the behavioral experiment will be used in MEG. Audience Effect experiment: trials will last for 7 seconds maximum. With 100 trials for each condition (public easy, public difficult, private easy and private difficult), the task will count a total of 400 trials and have a 47 minutes duration. Every 100 trials (about 12 minutes of tasks), a break will be proposed to the participants. Vicarious Reward experiment: trials will have a 7.2 seconds maximum duration. Using 75 trials for each condition (other low payoff, other high payoff, self low payoff, self high payoff, control condition), the task will have a total of 375 trials and last for 45 minutes. Every 125 trials (every 15 minutes), a break will be proposed to the participants.

Sponsors

Hospices Civils de Lyon
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Aged between 18 and 35 * Right-handed * French * Normal vision or corrected by contact lenses

Exclusion criteria

* Contraindications to the MEG examination * Presence of a perceptual disorder (vision) or motor impairing the capacity to carry out the tasks requested (including dyschromatopsia and achromatopsia). * Taking of medical treatment in progress (excluding contraceptive pill). * Known neurological or psychiatric history or disorders. * Participants in an exclusion period for any other research. * Participants who do not benefit from social protection. * Participants refusing to be informed of the results of the medical examination. * Participants who refuse to be informed of the possible detection of an anomaly. * Participants with MRI contraindications

Design outcomes

Primary

MeasureTime frameDescription
Modulation of the decisional parameter by the payoff conditions1 hourbehavioral data (reaction-times and accuracy) are collected and the decision parameter can be estimated from them using Drift Diffusion Models
Modulation of the decisional parameter by the beneficiary conditions1 hourbehavioral data (reaction-times and accuracy) are collected and the decision parameter can be estimated from them using Drift Diffusion Models

Secondary

MeasureTime frameDescription
Event-Related potentials1 hourstudy of the time-locked brain activity
Time-frequency brain responses1 hourstudy of the oscillatory activity elicited in the brain
BOLD1 hourVariation of the blood-oxygen-level dependent (BOLD) signal

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026