Clinical Outcomes, General Surgery, Nutritional Support, Nutrition Assessment
Conditions
Brief summary
It is a study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation.
Detailed description
It is a multi-center prospective observational cohort study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation. The nutrition risk were evaluated by different methods. The nutrition support regimens and the clinical outcomes were recorded.
Interventions
OTHERno intervention
no intervention
Sponsors
Jinling Hospital, China
Peking Union Medical College Hospital
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University
Xijing Hospital
West China Hospital
Xinqiao Hospital of Chongqing
Second Affiliated Hospital, Zhejiang University, School of Medicine
Changhai Hospital
Shanghai 10th People's Hospital
The Second Affiliated Hospital of Harbin Medical University
The Affiliated Hospital of Qingdao University
First Affiliated Hospital of Kunming Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Informed consent of patients or their legal representatives to participate in this study. 2. patients undergoing selective operation without trauma
Exclusion criteria
1. Age: \<18 years old or \>80 years old 2. Discharge within 24 hours 3. Accept surgery at 8:00 next day 4. Withdraw of patient's informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Morbidity of infection | From date of patients enrollment until the date of infection documented from any cause, assessed up to 2 months. | Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Resting Energy Expenditure (REE) by Indirect Calorimetry | From date of patients enrollment until the date of patients discharge from hospital, assessed up to 2 months. | REE was measured by indirect calorimetry (Q-NRG®) on postoperative days 1, 3, and 5 under standardized fasting and resting conditions. |
| Nutrition indicator | From date of patients enrollment until the date of patients discharge from hospital, assessed up to 2 months. | albumin/prealbumin/transferrin/retinol binding protein/IL-6 |
| Length of stay in hospital | From date of patients enrollment until the date of patients discharged from hospital, assessed up to 12 months. | The length of patients stay in hospital. |
| Actual calories intake | From date of patients enrollment until the date of patients are subjected to operation, assessed up to 2 months. | The total energy patients received during the study |
| Mortality | From date of patients enrollment until the date of death from any cause, assessed up to 2 months after patients discharged from hospital. | All deaths reported in all enrolled patients. |
Countries
China
Contacts
PRINCIPAL_INVESTIGATORXinying Wang, PhD
Jinling Hospital, China
Outcome results
None listed