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Patient-ventilator Asynchrony During Noninvasive Ventilation Assessed Using Diaphragm Ultrasonography

Patient-ventilator Asynchrony During Noninvasive Ventilation Assessed Using Diaphragm Ultrasonography

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03114384
Acronym
ADULT
Enrollment
15
Registered
2017-04-14
Start date
2017-04-14
Completion date
2017-07-30
Last updated
2017-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diaphragm, Ultrasonography

Brief summary

Fifteen healthy subjects under non-invasive ventilation will be have a recording of surface electromyogram, measurements of airway flows and pressures as well as a continuous ultrasound. The provocation of leaks on the Ventilation circuit and expiratory trigger modulation will generate a number of asynchronies between the subject and the respirator. These records will help to assess the agreement between the detection of asynchronies using electromyography of the respiratory muscles (technique of reference) and the diaphragmatic echography. We will also compare the respective performance of two techniques of diaphragmatic exploration (excursion and thickening of the diaphragm). A sensitivity of Ultrasound technique of at least 90% will be interpreted as a satisfactory index of concordance.

Interventions

OTHERCreation and detection of patient-respirator asynchronies

The provocation of leaks on the Ventilation circuit and expiratory trigger modulation will generate a number of asynchronies between the subject and the respirator

Sponsors

Centre Hospitalier Saint Joseph Saint Luc de Lyon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Healthy volunteer (male or female) * Free and Informed Consent

Exclusion criteria

* Known pregnancy, parturient or nursing mother * Minor under 18 years of age * Major incapable * Non-affiliation to the social security scheme * Any history of respiratory pathology

Design outcomes

Primary

MeasureTime frameDescription
Asynchronies detection with diaphragm ultrasonographythirty minutesEvaluation of the agreement between asynchronous subject-ventilator detection using diaphragm ultrasonography and detecting the same events in using the electromyogram of the respiratory muscles (as a reference technique.

Countries

France

Contacts

Primary ContactGuillaume Carteaux, Dr
guillaume.carteaux@gmail.com+ 33 1 49 81 23 94
Backup ContactEmmanuel Vivier, Dr
evivier@ch-stjoseph-stluc-lyon.fr+33 4 78 61 88 18

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026