Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03113552

Acronym

IPPVM

Enrollment

1500

Registered

2017-04-13

Start date

2013-02-04

Completion date

2028-07-04

Last updated

2023-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mitral Plasty, Mitral Valve Prolapse

Brief summary

Mitral insufficiency (MI) accounts for 24% of adult valvulopathies and affects 7% of subjects older than 75 years. They are the second leading cause of valvulopathy in Europe. The most common etiology is the associated valvular prolapse. Mitral surgery remains the reference treatment for symptomatic MI. The success of this procedure depends on the mitral valve geometry and the location of the prolapse. The site of the prolapse, whether monovalvular, localized to the posterior or anterior leaflet, or bivalvular, influences the possibilities and probably the long-term results of the plasty.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients operated between 1988 and 2011 * Presence of a valvular prolapse diagnosed by echocardiography * Possibility of a complete clinical evaluation at the time of the initial echocardiography

Exclusion criteria

* Ischemic MI (including papillary muscle rupture) * Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease * History of cardiac surgery

Design outcomes

Primary

Measure	Time frame
Survival defines as the time between the date of surgery and the death or date of the last news	6 months

Countries

France

Contacts

Primary ContactCatherine SZYMANSKI, Dr

szymanski.catherine@chu-amiens.fr+33322455885

Outcome results