Acute Heart Failure
Conditions
Brief summary
The HILO-HF Registry is a single centre registry that will be performed to provide information on the usual baseline oxygen saturation (SpO2) in patients presenting to ED with a primary ED diagnosis of AHF
Interventions
None listed
Sponsors
University of Alberta
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients \>40 years of age presenting to the ED with AHF * With or without tested BNP * With or without admission to hospital for treatment of HF\\ * Patients must be recruited within the first 24 hours of presenting to the ED.
Exclusion criteria
* Patients on home oxygen * Patients with known prior hypercapnic failure (PaCO2\>50 mmHg) * Asthma * Primary pulmonary hypertension * Patients requiring urgent positive pressure ventilation or intubation or on \>10 L/min oxygen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in blood oxygen saturation levels from baseline to 72 hours | 72 hours |
Secondary
| Measure | Time frame |
|---|---|
| Dyspnea on visual analogue scale (VAS) to 72 hours | 72 hours |
| Change in global symptoms using Patient Global Assessment (PGA) measure to 72 hours | 72 hours |
| Change in Peak Expiratory Flow | 72 hours |
| Rate of patients with Worsening Heart Failure | 7 days |
| 30-day composite clinical event (all-cause mortality, HF readmission, days alive and out of hospital) | 30days |
Countries
Canada
Outcome results
None listed