Cerebral Saturation, Cognitive Impairment, Emergencies
Conditions
Brief summary
There is no study of the association between ScO2 and POCD in non-cardiac, thoracic or vascular surgery. The few studies found in cardiac, thoracic and vascular surgery show an incidence up to 50% with a variation of the ScO2 threshold which varies between 15 and 25% according to the studies. Age is the main risk of OCDD. The management of this pathology should be early to avoid loss of autonomy of the patient. Finding a relationship, if it exists, would therefore significantly improve the mortality and morbidity of the said patient.
Interventions
OTHERTo evaluate the relationship between oxygen saturation and the incidence of postoperative cognitive dysfunction in emergency surgery in elderly patients
Evaluate the relationship between oxygen saturation and the incidence of postoperative cognitive dysfunction in non-cardiac, thoracic and vascular emergency surgery in patients 65 years of age and older. The occurrence of POCD will be defined by the MMSE decrease of at least 4 points at 24, 48 or 72 hours
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 65 years * Non-cardiac, thoracic and vascular emergency surgery * Surgery under general anesthesia * ASA I, II or III * Simple information without consent * Patient affiliated to social security
Exclusion criteria
* Inability to understand * Patient under tutelage, or curatorship or deprived of public right * ASA IV * History of severe dementia MMSE \<20 * Personal or familial history of malignant hyperthermia * History of allergy or hypersensitivity to anesthetic products used * Contra-indication to Cisatracurium®: myasthenia gravis * Contra-indication to Sevoflurane® * Contra-indication to local anesthetics * Indication of use of a Ketamine®-type hypnotic (modification of the BIS) * Indication of use of nitrous oxide * History of cranial trauma * Neuromuscular pathology * Spinal anesthesia * Cardiac, thoracic or vascular surgery * Surgery not performed in emergency * Neurochirugia in the context of cranial trauma * Any surgery that does not allow the use of the NIRS (impossibility of positioning of the electrodes by the location of the surgical field).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of POCD | 72 hours |
Countries
France
Outcome results
None listed