Skip to content

Garlic With Lime Juice and Chlorhexidine Mouthwash

Evaluation of Garlic With Lime Juice and Chlorhexidine Mouthwash on Gingival Bleeding in Group of Egyptian Children: A Randomized Clinical Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03105960
Acronym
mouthwash
Enrollment
36
Registered
2017-04-10
Start date
2017-03-10
Completion date
2017-06-01
Last updated
2017-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Bleeding

Brief summary

the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.

Detailed description

the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque. 1. Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group. provide chlorhexidine to the second group. 2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria. 3. Asses gingival condition by asking patient. 4. Subjects will be instructed to rinse for 14 days, twice daily. 5. Morning after breakfast and night before going to bed. 6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse. 7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.

Interventions

DRUGgarlic with lime mouth wash

garlic with lime juice is herbal antimicrobial 10 ml (undiluted) for 30s and then expectorate for 14 days.o prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.

DRUGchlorhexidine

hlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Masking description

This was a double-blind study as the investigator was unaware about the sampling of the groups and study subjects were unaware about the mouthwash they were using

Intervention model description

A Randomized Clinical Trial parallel

Eligibility

Sex/Gender
ALL
Age
9 Years to 12 Years
Healthy volunteers
Yes

Inclusion criteria

1. Children aged between 9 and 12 years. 2. Children are having normal occlusion (no crowding), non-compromised oral health (brushed their teeth once-daily) using toothbrush and non-fluoridated toothpaste. And practicing no other oral hygiene measures. 3. Medically free history. 4. Absence of orthodontic appliances.

Exclusion criteria

1. History of current or recent (at least for the past 1 month) antibiotic usage or other medications. 2. Presence of Abscess, draining sinus, cellulitis, or other conditions requiring emergency dental treatment. 3. not willing to comply with the study.

Design outcomes

Primary

MeasureTime frameDescription
gingival bleading15 daybleeding of gingiva asses by yes or no

Secondary

MeasureTime frameDescription
Streptococcal count in saliva and plaque15 dayStreptococcal count in saliva and plaque

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026