Cancer, Walking
Conditions
Keywords
Cancer, Exercise, Physical Function
Brief summary
This study will determine if a structured walking intervention will help maintain or improve physical activity levels, physical function and quality of life in hematopoietic stem cell transplant patients.
Detailed description
The researchers will quantify the decline in physical function of HSCT patients using valid and reliable tests aimed to mimic activities of daily living, quantify cardiovascular health, and quantify muscle power declines. Also, patients will undergo a walking program during their hospitalization, which is designed to increase physical activity levels and maintain and improve physical function and quality of life. Additionally, using valid and reliable questionnaires, the researchers will gauge perception of exercise, quantify current exercise levels, determine preference of exercise programs and counseling, and measure differences in quality of life before and after HSCT treatment.
Interventions
OTHERWalk Training and Transplant
Subjects will receive free activity monitors and have three training sessions per week for the duration of their bone marrow transplant treatment
OTHERActivity Monitoring and Transplant
Subjects will receive free activity monitors for the duration of their bone marrow transplant treatment
Sponsors
University of Miami
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Be between 40 and 80 years of age * Willing and able to provide written informed consent in English * Ability to comprehend the purpose of the study * Be scheduled to receive an autologous or allogeneic hematopoietic stem cell transplant at Sylvester Comprehensive Cancer Center * Have an expected hospital stay of at least 2 weeks * Not currently be participating in an exercise training program
Exclusion criteria
* Dementia, altered mental status, or psychiatric condition * Received erythropoiesis-stimulating proteins within 4 weeks prior to enrollment * Comorbid conditions that would contraindicate exercise testing * Undergoing concurrent non-transplant-related chemotherapy or radiation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Physical Performance Test Battery | 10 minutes | Physical Function |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Assessment of Cancer Therapy: Bone Marrow Transplant Questionaire Related Quality of Life | 20 minutes | Health-related quality of Life |
| Patient Reported Outcome Measurement Information System | 20 minutes | Health Related Quality of Life |
Countries
United States
Outcome results
None listed