Skip to content

Prevalence of Replication of Human Herpes Virus 6 (HHV6) in Blood and Skin During Exanthemia, in Patients With Hemopathy. Is There a Correlation With the Etiology of the Exanthema?

Prevalence of Replication of Human Herpes Virus 6 (HHV6) in Blood and Skin During Exanthemia, in Patients With Hemopathy. Is There a Correlation With the Etiology of the Exanthema?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03102905
Acronym
REPLIPO
Enrollment
37
Registered
2017-04-06
Start date
2016-12-12
Completion date
2018-09-28
Last updated
2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exanthema, Hemopathy, HHV6

Brief summary

To look for the replication of HHV6 by PCR in the skin, in these patients with haemopathies presenting an exanthema. This will make it possible to evaluate the prevalence of the positivity of this PCR in the skin. Then the investigator can investigate whether there is an association between the positivity of HHV6 PCR in the blood and / or skin and the viral etiology of the exanthema. If this association exists, it will make it possible to improve the diagnosis in the context of the exanthema and thus to improve the therapeutic management of these patients.

Interventions

OTHERMeasurement of the prevalence of the positivity of cutaneous HHV6 quantitative PCR in the cohort studied.

To evaluate the prevalence of the positivity of HHV6 PCR in the skin, during the exanthema in patients hospitalized for haemopathy.

Sponsors

Centre Hospitalier Universitaire, Amiens
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Supported for any type of hemopathy. * Allograft, autografted or ungrafted haematopoietic stem cells * Having presented an exanthema during hospitalization, for which a cutaneous biopsy had been performed * Having had a blood test of the HHV6 virus by PCR at least within the previous 40 days or following the rash. * Age greater than or equal to 18 years * Patient informed of the protocol by post, not having refused within one month of sending the said courier.

Exclusion criteria

* Patient who refused the search. * Patient whose HHV6 PCR in the blood was carried out at a distance of more than 40 days from the skin biopsy.

Design outcomes

Primary

MeasureTime frame
Measurement of the prevalence of the positivity of cutaneous HHV6 quantitative PCR in the cohort studied.1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026