Gastrointestinal Disorder, Functional
Conditions
Brief summary
This cross-sectional survey study is to determine the prevalence of functional gastrointestinal (GI) disorders in the general population and to describe common triggers for food-related GI symptoms.
Detailed description
Functional gastrointestinal disorders, involving symptoms such as gas/bloating, diarrhea, constipation and abdominal pain, are estimated to impact between 35 and 45 million Americans, an overwhelming 15-20% of the population. These symptoms are responsible for upwards of 20 billion dollars in healthcare costs and extensive loss of quality of life for sufferers. Moreover, many patients suffer in silence, with 67% of subjects waiting more than a year before treatment, and 11% waiting over 10 years. Irritable bowel syndrome is the most prevalent functional gastrointestinal disorder, and several recent studies support the idea that dietary modifications may be key to alleviating this condition. The purpose of this study is to document gastrointestinal symptoms among the US population, as well as to ascertain awareness and utilization of dietary treatments that exist.
Interventions
None listed
Sponsors
TriHealth Inc.
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
\-
Exclusion criteria
* Visual impairment * Inability to read * Inability to understand English * Inability to use a computer to respond to questions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Most Common Triggers for Food-related GI Symptoms (Top 5) | During the past 3 months before the survey | Percentages for foods chosen as triggers ( a subject can check more than one answer - Bread, Oats, Chili, Corn, Onion, Garlic, Beans, Chocolate, Fried or greasy foods, Eggs, Soy, Red meat, Fish or shellfish, Dairy products, Nuts and seeds, Apples, Bananas, Citrus fruit, Alcohol, Coffee, Carbonated drinks, Sugar-free gum) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Self-reported Functional GI Disorders | During the past 3 months before the survey | Percentages of self-reported functional GI disorders ( a subject can check more than one answer - Acid reflux (GERD), Irritable bowel syndrome (IBS), Celiac disease, Inflammatory bowel disease - Crohn's or Ulcerative Colitis, Diverticulities, Gastroparesis, Leaky gut, small intestinal bacterial overgrowth (SIBO), None of the above) |
Countries
United States
Participant flow
Recruitment details
The online survey took place from 3/9/2017 to 3/11/2017 through SurveyMonkey® (Palo Alto, CA, USA). The survey was distributed securely to a representative sample of the US population. 1881 subjects responded to the survey with 1718 completing all the questions (91% completers).
Participants by arm
| Arm | Count |
|---|---|
| GI Symptoms Survey Population The Survey participants are men and women between the ages of 18 and 80 in the United States | 1,718 |
| Total | 1,718 |
Baseline characteristics
| Characteristic | GI Symptoms Survey Population |
|---|---|
| Age, Customized 18-30 years | 347 Participants |
| Age, Customized 31-45 years | 506 Participants |
| Age, Customized 46-60 years | 502 Participants |
| Age, Customized 61-80 years | 351 Participants |
| Age, Customized Prefer not to answer | 12 Participants |
| Race/Ethnicity, Customized African American/Black | 111 Participants |
| Race/Ethnicity, Customized Asian | 70 Participants |
| Race/Ethnicity, Customized Caucasian/White | 1365 Participants |
| Race/Ethnicity, Customized Hawaiian or Pacific Islander | 10 Participants |
| Race/Ethnicity, Customized Native American | 21 Participants |
| Race/Ethnicity, Customized Other | 100 Participants |
| Race/Ethnicity, Customized Prefer not to answer | 41 Participants |
| Region of Enrollment United States | 1718 participants |
| Sex: Female, Male Female | 911 Participants |
| Sex: Female, Male Male | 799 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 0 |
| other Total, other adverse events | 0 / 0 |
| serious Total, serious adverse events | 0 / 0 |
Outcome results
Primary
Most Common Triggers for Food-related GI Symptoms (Top 5)
Percentages for foods chosen as triggers ( a subject can check more than one answer - Bread, Oats, Chili, Corn, Onion, Garlic, Beans, Chocolate, Fried or greasy foods, Eggs, Soy, Red meat, Fish or shellfish, Dairy products, Nuts and seeds, Apples, Bananas, Citrus fruit, Alcohol, Coffee, Carbonated drinks, Sugar-free gum)
Time frame: During the past 3 months before the survey
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| GI Symptom Survey Population | Most Common Triggers for Food-related GI Symptoms (Top 5) | Fried or greasy foods | 881 Participants |
| GI Symptom Survey Population | Most Common Triggers for Food-related GI Symptoms (Top 5) | Dairy products | 494 Participants |
| GI Symptom Survey Population | Most Common Triggers for Food-related GI Symptoms (Top 5) | Beans | 469 Participants |
| GI Symptom Survey Population | Most Common Triggers for Food-related GI Symptoms (Top 5) | Chili peppers | 460 Participants |
| GI Symptom Survey Population | Most Common Triggers for Food-related GI Symptoms (Top 5) | Alcohol | 354 Participants |
Secondary
Self-reported Functional GI Disorders
Percentages of self-reported functional GI disorders ( a subject can check more than one answer - Acid reflux (GERD), Irritable bowel syndrome (IBS), Celiac disease, Inflammatory bowel disease - Crohn's or Ulcerative Colitis, Diverticulities, Gastroparesis, Leaky gut, small intestinal bacterial overgrowth (SIBO), None of the above)
Time frame: During the past 3 months before the survey
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Acid reflux (GERD) | 411 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Irritable bowel syndrome (IBS) | 161 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Celiac diseas | 23 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Inflammatory bowel disease | 33 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Diverticulitis | 72 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Gastroparesis | 26 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Leaky gut | 20 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | Small intestinal bacterial overgrowth (SIBO) | 12 Participants |
| GI Symptom Survey Population | Self-reported Functional GI Disorders | None of the above | 1116 Participants |