Tongji Maternal and Child Health Cohort

Conditions

Birth Outcomes, Breast Feeding, Diet Habit, Growth and Development, Maternal; Diabetes Mellitus, Affecting Fetus, Pregnancy Complications, Weight Gain

Brief summary

This is a population-based study to obtain data for the evaluation of current used recommendations for weight gain during pregnancy released by IOM (2007) and investigate the association between maternal diet and the health outcomes of mother and offspring.

Detailed description

This is an ongoing population-based prospective cohort study to obtain data for the evaluation of current used recommendations for weight gain during pregnancy released by IOM (2007) and investigate the association between maternal diet and the health outcomes of mother and offspring. 8649 pregnant have been recuited from the first trimester of pregnancy. All datas including the general information, sociodemographic facts, physical exam (body weight, height, blood pressure, etc), laboratory test (hemoglobin, glucose concentration, etc.) and dietary survey (FFQ, 24h food recall) have been collected during the cohort study. Blood sample leftover from the clinical use are remained and stored at -80℃for further measurements. Obstetric characteristics, maternal and perinatal outcomes have been observed and recorded. Growth and development paremeters such as weight, length and head circumference as well as disease information of infants have been collected , feeding pattern and feeding history will be surveyed. All data collected will be used for group analysis only and all private and individual records will be kept secret.

Man Kong, Chunrong Zhong, Qin Gao, Xuezhen Zhou, Renjuan Chen et al. (10 authors)

Diabetes/Metabolism Research and Reviews2023-03-235 citations

10.1002/dmrr.3637

The association of maternal vaginal bleeding and progesterone supplementation in early pregnancy with offspring outcomes: a prospective cohort study

Chunrong Zhong, Guoping Xiong, Lixia Lin, Qian Li, Xi Chen et al. (18 authors)

BMC Pregnancy and Childbirth2022-05-058 citations

10.1186/s12884-022-04711-1

Association of Maternal Dietary Patterns With Birth Weight and the Mediation of Gestational Weight Gain: A Prospective Birth Cohort

Yan Li, Xuezhen Zhou, Yu Zhang, Chunrong Zhong, Li Huang et al. (15 authors)

Frontiers in Nutrition2021-11-2611 citations

10.3389/fnut.2021.782011

Association of the maternal serum albumin level with fetal growth and fetal growth restriction in term-born singletons: a prospective cohort study.

Xiong T, Wu Y, Huang L, Chen X, Zhang Y, Zhong C, Gao Q, Hong M, Hu X, Yang X, Yang N, Hao L.

2021-10-207 citations

10.1016/j.fertnstert.2021.09.016

Inverse association of total polyphenols and flavonoids intake and the intake from fruits with the risk of gestational diabetes mellitus: A prospective cohort study.

Gao Q, Zhong C, Zhou X, Chen R, Xiong T, Hong M, Li Q, Kong M, Xiong G, Han W, Sun G, Yang X, Yang N, Hao L.

2020-06-1325 citations

10.1016/j.clnu.2020.05.053

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Inclusion criteria

* Pregnant women attending the first visit (\<16 weeks ) at at a maternity clinic in one of these following hospitals in Wuhan, China: HMCHH, CHW,WMCHH,JMCHH. Intention to visit the maternity clinic regularly in HMCHH or CHW or WMCHH or JMCHH. * Intention to eventually deliver in HMCHH or CHW or WMCHH. * The pregnant woman and her husband are Chinese.

Exclusion criteria

* Pregnant women on chemotherapy. * Exclude women on certain medications - e.g. psychotropic drugs. * Exclude women with significant medical conditions e.g. psychosis etc.

Design outcomes

Primary

Measure	Time frame	Description
Effect of weight gain during pregnancy on maternal and child health	During pregnancy, infancy period and childhood, assessed up to 120 months	To regularly measure the weight gains of pregnant women during pregnancy, and examine their association with maternal and child health.
Effect of factors in pregnancy and early postpartum period on maternal health	During pregnancy and postpartum period, assessed up to 12 months	To examine the role of maternal nutrition, lifestyle, emotional health, and other environmental factors in pregnancy or postpartum period that can influence future maternal risk of metabolic disorders and even lead to complications of pregnancy, such as gestational diabetes mellitus.
Influence of prenatal and early postnatal factors on child health	During pregnancy, infancy period and childhood, assessed up to 120 months	To examine the role of maternal nutrition, lifestyle, emotional health, breastfeeding, and other environmental factors in infancy that can influence the development of phenotypes in childhood which confer risk for later metabolic and mental disorders.

Outcome results