Vestibular Schwannoma
Conditions
Brief summary
Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging
Detailed description
The purpose of this study was to evaluate the response of Gamma Knife Surgery to Ktrans, Ve, and Vp, which are indicators of permeability map obtained from dynamic contrast enhanced (DCE) MRI in patients with vestibular schwannoma .
Interventions
None listed
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with vestibular schwannoma, who underwent gamma knife surgery and pre-op dynamic contrast enhanced (DCE) MRI * Patients with vestibular schwannoma, who received consent
Exclusion criteria
* In addition to the vestibular schwannoma, if the brain has other underlying or systemic disease * During the observation period, other treatments were performed other than gamma knife surgery * If patients have a contraindication to MRI (eg, pacemaker, cochlear implants, hemodynamically unstable) * Concomitant use of gadolinium MRI contrast agents (eg, renal insufficiency \[glomerular filtration rate \<30 ML / min\]), or if there was a side effect when using a contrast medium. * Adults with impaired ability to cope * If the images and medical records required for this study are not available or are not appropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor size change before and after surgery | pre-op, Immediately after surgery |
Secondary
| Measure | Time frame |
|---|---|
| In patients who underwent gamma knife surgery, the magnitude of tumor size change before and after surgery | through study completion, an average of 1 year |
Contacts
Primary ContactSeungHong Choi, MD,PhD
Outcome results
None listed